410 Medical, Inc., is a medical device company focused on the development of innovative technologies for the treatment of critically ill patients, today announced that it has raised $3.1 million in new financing.  This round of funding was led by the AIM Group, a rapidly growing angel investor network investing in transformative life science and technology products.  Other new investors in this round include the North Carolina Venture Capital Multiplier Fund, Kleinheinz Capital, and WakeMed Health & Hospitals, the health system where 410’s LifeFlow® technology was developed.  “WakeMed’s investment is particularly exciting as it highlights the positive impact that LifeFlow is having for patients,” said Kyle Chenet, President and Chief Executive Officer at 410 Medical.

410 Medical and WakeMed have collaborated since the inception of LifeFlow, a device used for emergent fluid resuscitation. The LifeFlow device was originally developed at WakeMed by physician Dr. Mark Piehl in response to an opportunity he saw to improve outcomes for critically ill patients and, in particular, children with sepsis and other forms of shock. “WakeMed is committed to innovation where it supports our mission of providing the best possible patient care,” said Denise Warren, WakeMed’s chief operating officer.  “LifeFlow is a great example of a new product that is improving health and economic outcomes for our patients and our hospital.”

After FDA clearance and successful initial evaluation in 2017, WakeMed implemented LifeFlow throughout its multi-hospital system.  It is used frequently to treat patients with septic shock, trauma and other emergency conditions with dangerously low blood pressure which can quickly lead to organ failure or death if not treated immediately.  LifeFlow is a simple tool for rapid delivery of a measured fluid bolus that can resolve hypotension and shock and produce a visible patient response in minutes.

“Since the introduction of LifeFlow, nurses have been able to reduce the time required to deliver an initial dose of IV fluid  by more than 50 percent,”  said Jennifer Farmer, nurse manager, WakeMed Children’s Emergency Department. “We can now obtain IV access, complete the fluid bolus and administer antibiotics all within the ‘Golden Hour’, which often leads to an immediate improvement in a patient’s condition.  As familiarity with LifeFlow increases among providers, it is becoming a standard for our sickest pediatric patients in the emergency department and is now even included in our pediatric crash carts.”