Expansion of Topical Wound Oxygen (TWO2) Product Family

Extends Treatment to Chronic Wound Patients with Larger Limbs, Venous and Diabetic Foot Ulcers

September 16, 2020

AOTI Inc. announced today an eagerly anticipated expansion of its unique multi-modality Topical Wound Oxygen (TWO2) therapy product family.

AOTI notes the addition of a new larger extremity-chamber to the company’s peripheral vascular disease (PVD) focused product line, allows for the application of TWO2 treatments for many more patients suffering from costly nonhealing chronic wounds. Especially addressing the needs of those with larger limbs, or with venous leg ulcers (VLU) being treated by conventional compression dressings (CCD) or UNNA boots, or those with diabetic foot ulcers (DFU) being offloaded using a total contact cast (TCC).

Each year more than 8 million people in the USA suffer from chronic wounds that are commonly associated with such endemic comorbid health conditions as Diabetes, Obesity and PVD. TWO2 therapy has been shown to be particularly helpful in treating edematous wounds, by providing cyclical-pressure oxygen to help reduce edema via noncontact compression. TWO2 treatments are applied at home without the need to remove gas permeable dressings, with oxygen diffusing easily through CCD, UNNA boots and TCC adjunctive treatments. TWO2 has been further shown to reduce inflammation and help combat infection, thereby stimulating angiogenesis, while promoting better quality collagen synthesis, resulting in more robust and durable wound healing for up to 36 months. (1, 2)

“Prescribers had requested a larger version of our extremity-chamber, so they could treat the nonhealing wounds of patients that simply could not fit into the medium-sized chamber, due to either the size of their limbs or because they were also being treated with other adjunctive therapies, such as total contact casting and conventional compression dressings. We heard this plea and responded quickly to expand our product range. We are proud to be able to now provide the proven durable-healing outcomes of TWO2 to many more chronic wound patients in combination with their mainstay treatments,” stated Dr. Mike Griffiths, CEO and Medical Director of AOTI Inc.

Once ordered by the prescriber and set-up by our dedicated care team, TWO2 therapy is easily applied daily by the patient at home, without the need for clinic visits related to its utilization. AOTI also provides the prescriber with complimentary “eyes on the wound” Telehealth feedback, allowing for both healing and wound protective care to be delivered safely for patients at home. Something that has been shown to be vitally important during the COVID-19 pandemic.


  1. Diabetes Care 2020;43:616–624 | https://doi.org/10.2337/dc19-0476
  2. Vascular and Endovascular Surgery; 47(1),30-37 (3) I https://doi.org/10.1177%2F1538574412467684
Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine provides breaking medical device / biotechnology news. Our subscribers include medical specialists, device industry executives, investors, and other allied health professionals, as well as patients who are interested in researching various medical devices. We hope you find value in our easy-to-read publication and its overall objectives! Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

More News!

The Evolut ™ FX+ TAVR system leverages market-leading valve performance with addition of larger windows to facilitate coronary access
The study was an analysis of AstraZeneca’s Phase 2 52-Week clinical trial of tralokinumab in patients with Idiopathic Pulmonary Fibrosis (IPF). The patient data from the trial was processed with Brainomix’s e-Lung tool. The tool is uniquely powered by the weighted reticulovascular score (WRVS), a novel biomarker that incorporates reticular opacities and vascular structures of the lung.
“Since the algorithm for matching patients with donors is changing across for all organs, this was a prime time to better understand whether transplant team decisions to accept a donated organ varied by patient race and gender,” she said. “We wanted to understand how the process of receiving a transplant after listing varied by race and gender, and the combination of the two, so that steps can be taken to make that process more equitable," said Khadijah Breathett, MD.
The Mount Sinai study found that primary care physicians’ approach reflects a dearth of evidence-based guidance for lung cancer screening shared decision-making in patients with complex comorbidities
This is the first ever transplantation of a genetically engineered porcine kidney into a living human recipient.

By using this website you agree to accept Medical Device News Magazine Privacy Policy

Exit mobile version