The Hematology Laboratory, Molecular Hematology Unit, at Sheba Medical Center, Israel’s largest medical center, is conducting a joint study utilizing Sequentify’s InfiniSeq™ Myeloid Malignancies Panel. This study involves leading clinicians from the Cancer Center Institute, Maccabi Healthcare Services, and Sheba Cancer Research Center, focusing on identifying Clonal Hematopoiesis of Indeterminate Potential (CHIP) in patients previously diagnosed with solid tumors. The results from this study aim to advance personalized medicine in oncology, potentially influencing future patient care protocols.
Sequentify’s myeloid malignancy panel is a highly effective tool for sequencing patients with myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML). The straightforward and efficient InfiniSeq library prep protocol is an ideal choice for laboratories aiming to enhance or expand their sequencing capabilities, whether they are upgrading existing workflows or establishing new ones.
Dr. Dan Dominissini, Director of the Diagnostic Division at Sheba Medical Center, commented: “We are thrilled to partner with Sequentify on this study. As one of Israel’s leading research institutes and hospitals, ranked #9 among the world’s best hospitals by Newsweek, Sheba Medical Center is committed to staying at the forefront of diagnostic innovation. Our ultimate goal is to deliver better, faster, and more cost-effective results to our patients.” As part of the study, all patients will undergo sequencing using next-generation sequencing (NGS) technology, with all procedures conducted at the Sheba Medical Center facility to ensure the highest level of accuracy and depth in identifying CHIP.
Sequentify’s InfiniSeq technology reduces sample preparation time to just 3.15 hours, from DNA extraction to sequencing, using a single-tube reaction. It supports full automation and significantly reduces costs. The patent-pending InfiniSeq technology is compatible with most sequencing machines and seamlessly integrates into any lab workflow.