InVivo Therapeutics Announces New Patient Enrollment into the INSPIRE Study at the Carolinas Medical Center

April 5, 2017

InVivo Therapeutics Holdings Corp. (NVIV) today announced that a new patient has been enrolled into The INSPIRE Study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold™ for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury) at the Carolinas Medical Center in Charlotte, NC. Domagoj Coric, M.D., of Carolina Neurosurgery and Spine Associates, Chief of Neurosurgery at the Carolinas Medical Center, and a member of the INSPIRE Study Steering Committee, performed the implantation with his partner, Byron Branch, M.D.

InVivo Therapeutics notes the surgery was performed approximately 42 hours after the injury occurred. Dr. Coric and Dr. William Bockenek, Chief Medical Officer at Carolinas Rehabilitation, are Co-principal Investigators at this site.

Dr. Coric said. “It has been rewarding to be a part of the INSPIRE study and to implant my sixth patient with the Neuro-Spinal Scaffold. The implantation procedure went well, and I look forward to following this patient’s progress.”

Mark Perrin, InVivo’s Chief Executive Officer and Chairman, said, “We now have 14 INSPIRE patients enrolled and in follow up, and we have announced three enrollments since March 5. We thank Dr. Coric and his team for their continued support and look forward to continuing to make progress toward full enrollment.”

Additional details can be found at the company’s ClinicalTrials.gov registration site: http://clinicaltrials.gov/ct2/show/study/NCT02138110

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