Irvine Scientific Launches New Xeno-free Medium for Hematopoietic Progenitor Cell Culture

This Week’s News in Review

This Week's News in Review! Medical Device News Magazine keeps our readers up-to-date on breaking industry news! Learn how Medical Device News Magazine can help...

New Research Shows Nearly Half of Elderly Suffer Decreased Mobility During Lockdown

In a survey of UK adults with parents over the age of 75, while over half (52%) of respondents remain worried about their parents catching Covid, 48 percent are concerned about parental loneliness, and 46 percent about their parents falling alone and not being able to get up or get help. This figure remained high even among those whose parents are in care homes, with 37% of respondents still most concerned about parents falling over.

American College of Cardiology Names Ravee Kurian COO/CFO

Kurian comes to ACC following a 20-year stint at Publicis Sapient, a leading technology and communications consultancy, where he led critical and sensitive digital transformation initiatives for Fortune 500 and U.S. federal clients.

Its serum-free, xeno-free formula reduces the risks of contamination associated with media containing serum or non-human, animal-derived components

Irvine Scientific today announced another addition to its expanding line of products to support stem and immunological cell therapies with the introduction of PRIME-XV® Hematopoietic Cell Basal Medium. This new formulation follows other media in the PRIME-XV line as it is another serum-free, xeno-free basal medium that specifically supports robust expansion of hematopoietic progenitors while maintaining their multipotency, or functional properties needed for cell-based therapies.

Hematopoietic stem and progenitor cells (HSPCs) give rise to all other blood cells, and therefore have therapeutic potential for the treatment of cancers such as leukemia and lymphoma, and non-malignant diseases such as sickle cell anemia or immune related disorders. However, to be effective there must be sufficient numbers of HSPCs that retain their progenitor cell properties, including self-renewal and multipotency, to provide successful therapies.

HSPCs are often obtained from the blood or bone marrow of donors and are rare (only 1 in 100,000 in peripheral blood cells and 1 in 10,000 in bone marrow). With numbers of cells in the 100’s of millions required for therapy the challenge has been obtaining sufficient numbers of HSPCs that maintain their progenitor cell properties to differentiate and mature into the various hematopoietic lineage cells needed for therapies.

“In ex vivo culture HSPCs tend to spontaneously differentiate over time making it difficult to obtain large numbers of multipotent cells,” explained Dr. Jessie Ni, Chief Scientific Officer, Irvine Scientific. “When supplemented with the appropriate cytokines, PRIME-XV Hematopoietic Cell Basal Medium is formulated to support robust expansion of cell numbers while maintaining high percentages of multipotent hematopoietic progenitor cells.”

Its serum-free, xeno-free formula reduces the risks of contamination associated with media containing serum or non-human, animal-derived components. PRIME-XV Hematopoietic Cell Basal Medium is manufactured using stringent raw material qualification and under Current Good Manufacturing Practices (cGMP) for consistency, reliability and to make the move from research towards clinical applications.



Dr Jonathan Slotkin Appointed to Peer Well Board of Directors

Alongside the appointment, PeerWell is launching its new clinical practice, PeerWell Health.

Zimmer Biomet Announces New Appointments to Executive Leadership Team

Wilfred van Zuilen Appointed as President of Europe, Middle East and Africa. Nitin Goyal, M.D. Appointed to Newly Created Role of Chief Science, Technology and Innovation Officer.

Subscribe to Medical Device News Magazine here.

Related Articles