No Carolina / NY / Florida
Ph: 561.316.3330

No Carolina | NY | Florida

Expansion of Topical Wound Oxygen (TWO2) Product Family

Extends Treatment to Chronic Wound Patients with Larger Limbs, Venous and Diabetic Foot Ulcers

Editor: What To Know

  • “Prescribers had requested a larger version of our extremity-chamber, so they could treat the nonhealing wounds of patients that simply could not fit into the medium-sized chamber, due to either the size of their limbs or because they were also being treated with other adjunctive therapies, such as total contact casting and conventional compression dressings.
  • We are proud to be able to now provide the proven durable-healing outcomes of TWO2 to many more chronic wound patients in combination with their mainstay treatments,”.
  • AOTI also provides the prescriber with complimentary “eyes on the wound” Telehealth feedback, allowing for both healing and wound protective care to be delivered safely for patients at home.

September 16, 2020

AOTI Inc. announced today an eagerly anticipated expansion of its unique multi-modality Topical Wound Oxygen (TWO2) therapy product family.

AOTI notes the addition of a new larger extremity-chamber to the company’s peripheral vascular disease (PVD) focused product line, allows for the application of TWO2 treatments for many more patients suffering from costly nonhealing chronic wounds. Especially addressing the needs of those with larger limbs, or with venous leg ulcers (VLU) being treated by conventional compression dressings (CCD) or UNNA boots, or those with diabetic foot ulcers (DFU) being offloaded using a total contact cast (TCC).

Each year more than 8 million people in the USA suffer from chronic wounds that are commonly associated with such endemic comorbid health conditions as Diabetes, Obesity and PVD. TWO2 therapy has been shown to be particularly helpful in treating edematous wounds, by providing cyclical-pressure oxygen to help reduce edema via noncontact compression. TWO2 treatments are applied at home without the need to remove gas permeable dressings, with oxygen diffusing easily through CCD, UNNA boots and TCC adjunctive treatments. TWO2 has been further shown to reduce inflammation and help combat infection, thereby stimulating angiogenesis, while promoting better quality collagen synthesis, resulting in more robust and durable wound healing for up to 36 months. (1, 2)

“Prescribers had requested a larger version of our extremity-chamber, so they could treat the nonhealing wounds of patients that simply could not fit into the medium-sized chamber, due to either the size of their limbs or because they were also being treated with other adjunctive therapies, such as total contact casting and conventional compression dressings. We heard this plea and responded quickly to expand our product range. We are proud to be able to now provide the proven durable-healing outcomes of TWO2 to many more chronic wound patients in combination with their mainstay treatments,” stated Dr. Mike Griffiths, CEO and Medical Director of AOTI Inc.

Once ordered by the prescriber and set-up by our dedicated care team, TWO2 therapy is easily applied daily by the patient at home, without the need for clinic visits related to its utilization. AOTI also provides the prescriber with complimentary “eyes on the wound” Telehealth feedback, allowing for both healing and wound protective care to be delivered safely for patients at home. Something that has been shown to be vitally important during the COVID-19 pandemic.


  1. Diabetes Care 2020;43:616–624 | https://doi.org/10.2337/dc19-0476
  2. Vascular and Endovascular Surgery; 47(1),30-37 (3) I https://doi.org/10.1177%2F1538574412467684
Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine provides breaking medical device / biotechnology news. Our subscribers include medical specialists, device industry executives, investors, and other allied health professionals, as well as patients who are interested in researching various medical devices. We hope you find value in our easy-to-read publication and its overall objectives! Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

Recent News

CV Societies Propel Plans Forward for a New Board of Cardiovascular Medicine

“The open comment period is the time for cardiovascular physicians, allies in other medical specialties, patients, and others to make their voices heard on why an independent CV Board is the best path for cardiologists to stay up-to-date on best practices and evidence-based care, ensuring patients receive the best possible care,” said Jeffrey Kuvin, MD, president of the proposed Board’s new Board of Directors. “The field of cardiovascular medicine has evolved dramatically over the past few decades; now is the right time to develop an independent cardiovascular Board.”

Hyundai Bioscience Announces Clinical Development Plan for Niclosamide-based Metabolic Anticancer Drug Targeting P53 Mutation Cancer

Sang-ki Oh, CEO of Hyundai Bioscience, stated, "Niclosamide-based metabolic anticancer drug candidate will be the first P53-targeting anticancer treatment that selectively kills p53 mutated cancer cells," and added, "Through our subsidiary ADM Korea, we plan to conduct clinical trials targeting cancer patients with intractable cancer caused by p53 mutations, which will be the first step of clinical development on niclosamide-based anticancer agent pipeline."

Sedana Medical Completes Patient Recruitment for INSPiRE-ICU 1 Clinical Trial in the US

Peter Sackey further elaborated: "Once the 30-day follow-up of all patients is complete, we will enter into an intense phase of final monitoring, data cleaning and transfer to our statistician team for analysis. In parallel, the long-term outcomes at 3 and 6 months will be collected centrally by the Critical Illness, Brain Dysfunction, and Survivorship team at Vanderbilt Medical Center. With this parallel approach, we expect topline results in the autumn of this year and a swift regulatory submission in Q1, 2025".

Health / Lifestyle

Articles of Interest

Stay Connected

spot_img

About Medical Device News Magazine

About Medical Device News Magazine. A digital publication founded in 2008 located in the United States. The publication is one of the industry’s leading sources of medical device and biotech industry updates. Medical Device News Magazine is easily accessible 24/7/365 and is a fast 1, 2, 3 easy read! Our purpose is...

By using this website you agree to accept Medical Device News Magazine Privacy Policy