“During the autumn, we have visited several of our active eye clinics in the US and we are experiencing great enthusiasm after the promising signals of effect. We also see an increase in recruitment rates after we changed the study protocol and removed the placebo group. We remain committed to our plan to have all patients included in the study during the first quarter of next year and to be able to report 4-month follow-up data thereafter”, says Dr. Anna Frostegård, Chief Scientific and Medical Officer at Annexin Pharmaceuticals.

PK051 is a combined drug that targets disaggregates of amyloid-β proteins. There is increasing scientific acceptance that overproduction and/or deposition of amyloid-β is the initial event in Alzheimer’s Disease pathology.

“The data from this study show a correlation between the expansion of TIL-specific clones and tumor response, which provides compelling support for the use of pelareorep-based therapies in immunologically “cold” tumors. In particular, these data, along with the impressive clinical results, support the ability of pelareorep-checkpoint inhibitor combination therapies to meaningfully improve treatment responses in diseases like pancreatic cancer that have resisted immune-based therapeutic approaches,” said Thomas Heineman, M.D., Ph.D., Chief Medical Officer at Oncolytics Biotech.

“Ulcerative colitis is a complex immune-mediated disease that can cause a wide range of often-debilitating symptoms,” said study author Jessica R. Allegretti, M.D., Medical Director, Crohn’s and Colitis Center at the Brigham and Women’s Hospital, Boston, MA, USA.c “Results from the QUASAR studies support the potential of TREMFYA as a durable and fast-acting treatment option.”

Diazepam nasal spray is Japan’s first nasally administered antiepileptic that has demonstrated efficacy and safety in Phase 3 clinical trials in Japan for the treatment of status epilepticus or epileptic seizures that may lead to status epilepticus.