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Recursion Notes Dr Michael Secora Appointed CFO

Dr. Michael Secora will focus primarily on the Recursion’s fundraising and strategic finance events and will leverage his decade-plus of experience investing at the intersection of biology and technology.

“Decoding biology to radically improve lives is a bold ambition that requires substantial investment in a capital-intensive and revenue-deferred industry. We must be strategic in how we finance our company and achieve that ambition,” said Chris Gibson, Ph.D., Co-Founder and CEO, of Recursion. “Michael brings that forward-looking, strategic finance perspective to Recursion. He has evaluated and invested in approximately 900 IPOs mostly in biopharma and tech and knows what makes a company attractive to the markets. I am extraordinarily excited for how his expertise and innovative thinking will support our goal of continuing our buildout of the industry’s leading digital biology company.”

Before joining Recursion, Dr Michael Secora was Managing Director and Head of Capital Markets and Venture at Laurion Capital, an asset manager based in New York City who has been influential within the capital markets complex. He received his Ph.D. from Princeton University in Applied and Computational Mathematics and B.S. degrees from MIT in Mathematics and Physics. A self-proclaimed “student of the capital markets” with a scientific background, Michael has closely observed the emergence and evolution of technology-enabled drug discovery over the past few years, having worked with and invested in companies in that sector. However, Michael ultimately decided to join Recursion after spending 10 years at Laurion.

“I believe that we are at an important time in history where the advances in biotechnology in the next half-century may eclipse advances made in silicon and computational technology in the previous half-century. Moreover, I believe that this novel field of technology-enabled drug discovery has transformative potential for the cost and time to develop therapeutics as well as improving the quality of life for people suffering from disease,” said Dr. Secora. “To that end, I think that Recursion is best positioned to enact this vision and industrialize drug discovery. It is with passion that I accept the invitation to become Recursion’s CFO and bridge conventions in the fields of technology and biotechnology while innovating the means to capitalize.”

Team in Toronto and Winnipeg to Begin Production of Medical Scrubs and Patient Gowns

Canada Goose reports they will begin making scrubs and patient gowns, which are in short supply across the country, and will begin distributing them to hospitals next week.

To help address the urgent need facing healthcare workers and patients across the country, Canada Goose has committed to producing medical gear at two of its manufacturing facilities, starting in Toronto and Winnipeg, with the opportunity to extend production across additional facilities as needed. With production set to begin early next week, approximately 50 employees per facility will work to manufacture the gear and have an initial goal of producing 10,000 units.

“Across Canada, there are people risking their lives every day on the frontlines of COVID-19 in healthcare facilities, and they need help. Now is the time to put our manufacturing resources and capabilities to work for the greater good,” said Dani Reiss, President & CEO, Canada Goose. “Our employees are ready, willing and able to help, and that’s what we’re doing. It’s the Canadian thing to do.”

The company is working closely with federal, provincial and local health authorities and will follow the recommended protocols to ensure a safe work environment for employees, including implementing social distancing protocols, limiting the number of employees located within specific spaces, and increasing sanitation measures within facilities to ensure the health and safety of team members.

Canada Goose Response Program COVID-19 Initiatives to date:

  • Production of Personal Protective Equipment: Beginning week of March 30th, Canada Goose will manufacture scrubs for healthcare workers as well as patient gowns. The gear will be donated locally at no cost, with the goal of providing as much equipment as possible to those in need.

  • Canada Goose Employee Support Fund: On March 17th the Canada Goose Employee Support fund was established for employees who are impacted by store and manufacturing closures but are not eligible for government assistance. In a letter to Canada Goose employees, Dani Reiss announced that he will forego his salary for at least the next three months, which will be used for the Employee Support Fund. 

  • Wuhan Charity Donation: On February 6th Canada Goose announced a RMB1 million donation to the Wuhan Charity Federation to help fight the COVID-19 outbreak. The Wuhan Charity Federation is a non-profit organization designated by the Wuhan City Epidemic Prevention and Control Headquarters to receive donations for relief efforts.

Other device and supply news can be found here.

Enrollment in Tria LifePolymer Early Feasibility Study Completed: Included 15 Patients

Tria LifePolymer

March 25, 2020

Enrollment in Tria LifePolymer study includes fifteen patients’ reports FOLDAX® at four participating sites.

“The study is progressing well and we will be reporting on the early clinical experience later this year,” stated Amit Patel, MD, MS, the principal investigator of the study.

The aortic EFS is the first in a series of clinical studies Foldax will be conducting on its Tria LifePolymer heart valve line. LifePolymer is a patented polymer formulated specifically for heart valve application with the goal of enhancing durability, hemodynamic performance and providing exceptional value over current heart valves. The next studies will focus on surgical mitral valve and transcatheter aortic valve applications.

“This accomplishment would not be possible without the significant contributions of our clinical investigators and their teams at Ohio Health in Columbus, The Christ Hospital in Cincinnati, St. Vincent’s in Indianapolis and Beaumont Hospital in Detroit. We are looking forward to initiating our surgical mitral and TAVR clinical studies to continue our goal of transforming heart valve therapy,” stated Ken Charhut, Foldax Executive Chairman.

 

ACS Releases New Clinical Guidance Document for Elective Surgical Case Triage during COVID-19

The American College of Surgeons (ACS) continues to provide guidance for surgeons to curtail recommendations for elective surgical procedures to preserve the necessary resources for care of critically ill patients during the COVID-19 pandemic.

To assist in surgical decision-making in curtailing cases, ACS has released “COVID-19: Elective Case Triage Guidelines for Surgical Care,” a new surgical triage document that was developed following expert review in several specialties and provides trusted information from the most current best evidence available in the following areas:

These triage recommendations should be used in conjunction with a joint statement ACS has developed with the American Society of Anesthesiologists and the Association of periOperative Registered Nurses recommending medical centers develop a Surgical Review Committee to act as an administrative body to provide defined, transparent, and responsive oversight for triaging surgical cases during the COVID-19 pandemic.

The ACS, ASA, and AORN recommend decisions of the Surgical Review Committee regarding surgical cases be made on a daily basis, no later than the day before an operation, and should include a multidisciplinary leadership team representing surgery, anesthesiology, and nursing.

“These triage guidelines and joint recommendations are being issued as we appear to be entering a new phase of the COVID-19 pandemic with more hospitals facing a potential push beyond their resources to care for critically ill patients. ACS will continue to monitor the landscape for surgical care but we feel this guidance document provides a good foundation for surgeons to begin enacting these triage recommendations today to help them make the best decisions possible for their patients during COVID-19,” said ACS Executive Director David B. Hoyt, MD, FACS.

 

Telehealth Virtual Visits Software is Launched by Seattle Based MedBridge

The offer is intended to provide crucial help to healthcare organizations and their patients throughout the COVID-19 crisis by allowing providers to manage the care of their patients remotely.

Healthcare organizations and professionals across the care continuum are now being confronted with equally difficult challenges. Many outpatient organizations are experiencing steep revenue loss as patients cancel or defer appointments due to quarantine, social distancing protocols, and concerns overexposure. Post-acute care clients, including those in skilled nursing and home health, must adjust care delivery to keep both their staff and patients safe. In response, MedBridge launched its Telehealth solution to be available as a beta version several months sooner than planned.

MedBridge is here to support our customers, their patients, and their communities during this challenging time and beyond. We’re committed to helping everyone weather this crisis and stay prepared during every stage with innovative solutions for remote care and education as we all adjust to a new paradigm,” said Justin Kowalchuk, CEO, and founder of MedBridge.

MedBridge Telehealth allows providers to remotely screen, triage, and care for patients in real-time, providing a HIPAA-compliant method for continuing treatment plans during the ongoing COVID-19 crisis. Providers can also foster rapport, engagement, and education by building, sharing, and discussing targeted home exercises with their patients during each virtual visit.

“Telehealth Virtual Visits offers a patient experience that’s as close as possible to an in-person session. It’s easy to implement, use, and learn for clinicians and patients, which is essential now that healthcare professionals are in crisis mode. Because it allows for uninterrupted care, it can be used to optimize long-term outcomes by rehab providers across the care continuum,” said Keta Shaw, Telehealth Product Manager, MedBridge.

The Virtual Visit software is part of the complete MedBridge Digital Patient Engagement Suite, which includes program adherence tracking, in-app messaging, and satisfaction monitoring to help patients self-manage and stay active in their plan of care while they’re confined to their home. The virtual patient care solution, paired with MedBridge’s remote training, infection prevention, and crisis management education, offers healthcare organizations a complete solution to combat the challenges of this time.

SaniCart Mobile, Micro-Fogging Sanitation System, When Paired with an EPA-Approved COVID-19 Disinfectant, Can Kill Coronaviruses in the Air and on surfaces

The fog produced by SaniCart engulfs enclosed areas with a cloud of disinfectant that remains suspended in the air and covers all surfaces for complete disinfection.

SaniCart patented nozzle creates a micro-fog to achieve this breakthrough air and surface disinfectant coverage in the fight against COVID-19.

“The EPA has released List N: Disinfectants for Use Against SARS-CoV-2. SaniCart is the missing puzzle piece as it simplifies and automates the process of effectively applying these sanitizing agents. Since SaniCart can operate with a wide range of disinfectants, we have ramped up manufacturing to provide this vehicle to the frontlines, including hospitals, ambulances, grocery stores and government agencies, to keep their facilities sanitized and protect their workers while they continue to serve us during this immediate time of crisis,” said Nadya Merchant, M.P.H., PhD., Scientific Director at Aguair LLC.

Last week Aguair partnered with TwinOxide Inc., whose chlorine dioxide (EPA Reg. No. 86054-1) is safe and effective against many resistive strains of pathogens and viruses, including coronaviruses.

“When SaniCart was used to dispense TwinOxide, we were able to quickly achieve and maintain the EPA-prescribed concentration of chlorine dioxide throughout the test environment, thereby killing any coronaviruses that might be present in the air and on surfaces,” said Dr. Joe Nieusma of TwinOxide.

Recent studies have shown that COVID-19 remains suspended as droplets in air for up to three hours, after which it settles onto surfaces and can survive for multiple days. SaniCart addresses this lifecycle of COVID-19 by thoroughly fogging the air and covering surfaces, including nooks and crannies, to completely disinfect any enclosed area. SaniCart provides the user with an efficient automated process that can be implemented by just rolling the cart into a room and pressing the start button to deliver any disinfectant of choice.

Aguair and its parent company, Prodew Inc., are utilizing SaniCart and their ClensAir air purifier to disinfect and maintain sanitation in their own facilities. In this way, they are providing their workers with a more sanitized environment so that they can continue to manufacture and meet the increased demand for this vital equipment from their customers.

KN95 Disposable Masks Now Available on Avenova.com

KN95 disposable masks are being sold at a price of $59.99 for a package containing 10 masks or $149.99 for a package containing 30 masks. KN95-rated masks are effective at filtering out at least 95% of airborne particles, including microorganisms, dust, pollen and air pollution.

“In light of the shortage of protective masks, we have tapped into our global health supplier network to procure and make available a high-quality, KN95-rated product at the most reasonable price possible,” said Justin Hall, NovaBay CEO. “We received our first shipment of KN95 masks last week, which sold out online very quickly and expect a second large inventory of masks to be available for shipment today. To meet the immediate need, we had the masks flown in on a rush basis. We have direct access to a large supplier of KN95 masks and encourage organizations ordering quantities of 50,000 or more to contact us directly at 1-800-890-0329 for special pricing.

“We plan to continue providing KN95 masks on Avenova.com for as long as the demand remains,” Mr. Hall added. “In these most unusual of circumstances, it’s gratifying for the NovaBay team to carry out our commitment to marshal all of our talents and resources to benefit the health and wellbeing of people everywhere. We will continue to be here to help accomplish this objective during and after this crisis is over.”

The NK95 disposable masks are constructed with a three-layer filtration system of nonwoven soft and breathable fiber for effective protection. The masks feature extra soft and comfortable elastic ear loops that will not apply pressure to the ears during use and have an adjustable nose bridge strip. The masks come in a single size that fits most faces. They are non-toxic, odorless, non-irritating, contain no dyes and are hypoallergenic and gentle on the skin. The disposable masks should be replaced daily for best hygiene and are ideal for one-time use in a non-medical setting.

The KN95 air filter masks are manufactured by Earntz Nonwoven Co., Ltd. and are CE certified for FFP2 protective mask (EN 149-2001) and meet KN95-level requirements (GB 2626-2006).

Dr Deborah A Jeffries New Tryten Global Director of Healthcare

Dr Deborah A Jeffries is Tryten new Global Director of Healthcare. Dr. Deborah A. Jeffries (Dr. Deb) brings 25 years of expertise in medicine, education, telehealth, video conferencing, virtual training, patient care, and healthcare industry trends.

Dr. Deb did undergraduate and post-graduate work in physics at UCLA. She received her ND from NCNM. She taught pathology at NCC, as well as pathophysiology and hematology at Merrimac College.

Dr. Deb will be helping Tryten to launch multi-purpose (video-capable) cart/vehicles for telemedicine encounters, video remote interpreting, patient observation, and electronic health record workstations.

“It is so exciting to join the team at Tryten. Today the healthcare system is challenged like never before. Not only are we experiencing a major paradigm shift to healthcare that is focused on workflow efficiencies, practitioner availability, patient-centered care, digital health, and cost containment, but now we are faced with a rapidly evolving pandemic and how to respond to COVID-19 and the multiple complexities it brings. We need to immediately focus on how to help.”

Tony Janzen, founder, and CEO of Tryten states, “We are excited that Dr. Deb has joined our growing team. Dr. Deb brings a level of professionalism and knowledge that makes her so valuable to the growth and development of Tryten.”

Dr. Deb will be focused on healthcare solutions and supporting Tryten’s marketing and sales efforts.

University of Helsinki and IRRAS Will Collaborate to Advance Uses of IRRAflow

IRRAS has announced a long-term collaboration with Dr. Nika Niemela, Professor and Chairman of Neurosurgery, and Dr. Behnam Rezai Jahromi from the University of Helsinki, one of the world’s leading neurosurgical institutions, to utilize the company’s IRRAflow system in a variety of neurocritical applications.

IRRAS notes The initial area of focus will be in the treatment of patients suffering from intraventricular hemorrhage (IVH).

IRRAflow is the world’s first “irrigating intracranial drain,” and its unique mechanism of action addresses the complications associated with the current methods of managing intracranial fluid by using a dual-lumen catheter that combines automated irrigation, controlled drainage, and continuous ICP monitoring, all into one system. IRRAflow was introduced into the U.S. market in 2019 following the receipt of 510(k) clearance by the United States Food and Drug Administration (FDA) and is currently being reintroduced into the European Union (EU) after the recertification of the system’s CE Mark in December 2019.

“It is my belief that the system’s combination of automated irrigation and controlled drainage should contribute to better long-term outcomes for these critically ill patients, and I am excited to explore that hypothesis in greater detail,” said Dr. Mika Niemelä. “My early experience with the IRRAflow system has shown impressive acute results in draining collected toxic material out of the ventricles without catheter blockages,” said Dr. Rezai Jahromi.

Traditional treatment options for IVH patients generally utilize an External Ventricular Drainage (EVD) system, which is a passive approach that relies solely on gravity to facilitate drainage. Although an EVD is currently the most common treatment option for intracranial bleeding or elevated ICP, the technology is associated with several well-known complications such as catheter blockage, infections, and incomplete drainage. All of these complications can negatively impact patient outcome, which can subsequently increase the length of time needed in the hospital and the overall cost of care.

HUH Neurosurgery is world-famous for its expertise in all subsections of neurosurgery. It is considered the leading center in Europe in the microneurosurgical treatment of cerebral blood vessel diseases and complex brain tumors and is also ranked among the very best units in the world. Due to this reputation as one of the world’s leading centers in cerebrovascular problems, some of the most complex cases in the field are referred to Helsinki from other parts of the world. Each year, more than 3,200 patients undergo neurosurgical treatment at Helsinki, and nearly 200 neurosurgeons from all around the world visit the facility to learn the latest techniques in neurosurgery.

“This collaboration with Dr. Rezai Jahromi and the University of Helsinki represents an important component of our launch strategy for IRRAflow,” said Will Martin, Chief Commercial Officer of IRRAS. “There is a compelling need for transformative technologies, such as IRRAflow, to treat patients with intracranial bleeding, and we believe that this collaboration will advance the treatment of IVH and also accelerate the product’s awareness to a wider group of neurocritical care specialists.”

ixlayer COVID-19 Clinical Test Platform to Power Labs and Health Systems Launched

ixlayer reports they adapted its platform to address the need to rapidly launch and scale COVID-19 clinical testing.

The ixlayer COVID-19 Clinical Test Platform already encompassing the security components that are complex and time-consuming to deliver, has been adapted for COVID-19 specific content and user flows, allowing physicians/health systems, organizations, and university groups to quickly connect with partnering labs to deliver COVID-19 clinical testing.

“When the World Health Organization declared rapid and global testing was needed to address COVID-19, I knew that would present challenges. Bringing a new test online can be complicated and time-consuming without technology solutions. Thankfully, the ixlayer platform has been efficiently delivering precision health testing across the U.S. using the telehealth model for several years, so we already have the needed security and infrastructure in place,” said Pouria Sanae, CEO of ixlayer COVID-19 Clinical Test Platform. “I am proud of my team’s swift modifications to the ixlayer platform, ensuring the additional measures needed to scale COVID-19 testing nationally are in place.”

Learning from the global responses to COVID-19, ixlayer made sure the platform addressed the issues facing U.S. clinical labs including:

  • Scalable technology to support multiple labs and providers across all states,
  • Telemedicine infrastructure so ordering physicians can connect with patients at home,
  • Secure online (HIPAA compliant) collection of patient health screening and eligibility data,
  • Third-party Telemedicine physician networks to support high demand, and
  • Ability to schedule COVID-19 sample collection for patient drive-through.

The ixlayer platform has specific user flows and content for each type of relationship, connecting clinical laboratories to:

  • Organizations,
  • Employee groups, and
  • Physicians/health systems.

For example, physicians order tests on the platform using their NPI number. Employee groups or researchers can access the platform through a clinical portal to order tests. Patients can also directly request testing by logging in to the secure Patient Portal and completing a Health Screening Eligibility Questionnaire that evaluates their current symptoms, recent travel, and community exposure to COVID-19. They then provide the contact information for their healthcare provider and the platform reaches out to the provider to review the patient’s request and determine if the test is a good fit for their present situation.

The COVID-19 Clinical Test platform also gathers real-time data, including demographics on positive and negative tests by age, gender and geographic location – allowing the Centers for Disease Control or other researchers to identify trends in disease transmission. In addition, if a large number of inconclusive or “no-call” results are present in a given area, issues with the testing pipeline can be identified and addressed rapidly.

Finally, content throughout the platform was thoughtfully developed, using CDC and WHO guidelines, to ensure patients have accurate, up-to-date educational materials. The content is evaluated and adjusted regularly, as CDC and WHO guidelines and recommendations evolve. It can also be customized for an individual group’s specific needs while maintaining the integrity of the message from these leading authorities.

“We can support not only the infrastructure and technology issues of the clinical labs and healthcare system, but also deliver metrics to help researchers model and learn from disease trends. Now, employee groups can also order bulk testing to clear employees, so only the healthy are in essential positions,” said Pouria Sanae, CEO of ixlayer. “I hope our platform can help connect the critical pathways in the national health ecosystem working diligently to combat COVID-19.”