Translumina Launches VIVO ISAR, its Dual-Drug Polymer-free Coated Stent in International Markets

Translumina, a global developer and manufacturer of innovative cardiovascular medical devices used in interventional cardiology, announces the launch of VIVO ISARits latest generation dual drug polymer-free coated stent (DDCS), in various International markets including Europe.

As an organization, Translumina has always been synonymous with innovation in the field of intervention cardiology and today’s announcement further strengthens its global cardiovascular portfolio.

Several studies have proven that polymers are pro-inflammatory and may cause stent thrombosis. However, the use of polymers has been necessary in current generation DES as they control the release kinetics of the drug by acting as a carrier for drug loading and release.

VIVO ISAR is the first Dual Drug Polymer-Free Coronary Stent technology, which brings together a stent with a superior safety profile without compromising the drug release kinetics. VIVO ISAR is the first technology that uses Probucol, an antioxidant and lipid-lowering drug, as a carrier for releasing Sirolimus (an anti-restenotic drug) and thus creates a polymer-free DES platform with uncompromised safety and efficacy.

In 2020, Translumina became the only company in the world to publish 10-year follow-up data on its Dual-Drug Polymer-free Coated Stent (DDCS) VIVO ISAR. The Journal of the American College of Cardiology (JACC), which is amongst the top publications in the world of cardiology, with a high impact factor as per Journal Citation Reports, published the 10-year safety and efficacy follow-up data on VIVO ISAR.

“The ten-year outcome of VIVO ISAR is a major breakthrough in DES technology as it proves that synthetic polymers can be removed from a DES without compromising the efficacy of the DES. The excellent safety profile demonstrated in the 10-year follow-up study is especially notable as it provides a powerful new technology for treating complex coronary artery disease in high-risk patient subsets. This DES technology carries the great potential of significantly shortening the duration of dual antiplatelet therapy,” said Dr Adnan Kastrati, Director, Cardiac Cath Lab, German Heart Center, Munich and the lead investigator of ISAR TEST 5, the trial that compared VIVO ISAR to Endeavour Resolute (Medtronic Inc USA).

Patients with diabetes mellitus present a particular challenge as the disease is associated with a more diffuse manifestation and consequently suboptimal clinical outcome after percutaneous coronary intervention.

In 2021, the Journal of American Heart Association published compelling 10-year efficacy and safety data of VIVO ISAR in a Diabetes subset highlighting its excellent efficacy and safety profile, with 30% reduction of MI as compared to Endeavour Resolute. Translumina became the first company in the world to achieve the longest RCT follow-up with its flagship Dual Drug Eluting Stent that brings new hope for the high-risk diabetic subset.

Translumina has launched VIVO ISAR in Italy & Spain and plans to roll it out in several markets across Europe, Latin America and APAC over the coming months.

“We are very pleased to be able to provide our premium high-quality stents to customers across the globe. Cardiologists world over now have a choice to give a proven and safer Drug Eluting Stent to their patients who otherwise have poorer outcomes with conventional DES, more so among the high-risk diabetic subset,” said Gurmit Singh Chugh, MD and Co-founder, Translumina.

Everstone Capital invested in Translumina in 2019 to further strengthen its research & development pipeline, scale its manufacturing operations and expand its global footprint to transform Translumina into a leading multinational medical devices company.

“We are proud that Translumina is leading the global journey of creating the highest standards of clinical data that enable physicians to treat patients with more confidence and certainty,” said Dr. Arjun Oberoi, Managing Director, Everstone Capital.

Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine provides breaking medical device / biotechnology news. Our subscribers include medical specialists, device industry executives, investors, and other allied health professionals, as well as patients who are interested in researching various medical devices. We hope you find value in our easy-to-read publication and its overall objectives! Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

More News!

The Evolut ™ FX+ TAVR system leverages market-leading valve performance with addition of larger windows to facilitate coronary access
The study was an analysis of AstraZeneca’s Phase 2 52-Week clinical trial of tralokinumab in patients with Idiopathic Pulmonary Fibrosis (IPF). The patient data from the trial was processed with Brainomix’s e-Lung tool. The tool is uniquely powered by the weighted reticulovascular score (WRVS), a novel biomarker that incorporates reticular opacities and vascular structures of the lung.
“Since the algorithm for matching patients with donors is changing across for all organs, this was a prime time to better understand whether transplant team decisions to accept a donated organ varied by patient race and gender,” she said. “We wanted to understand how the process of receiving a transplant after listing varied by race and gender, and the combination of the two, so that steps can be taken to make that process more equitable," said Khadijah Breathett, MD.
The Mount Sinai study found that primary care physicians’ approach reflects a dearth of evidence-based guidance for lung cancer screening shared decision-making in patients with complex comorbidities
This is the first ever transplantation of a genetically engineered porcine kidney into a living human recipient.

By using this website you agree to accept Medical Device News Magazine Privacy Policy

Exit mobile version