Knee Arthritis Made Worse with Steroid Injections

“The most striking finding is that a single corticosteroid injection led to significantly greater structural damage in the knee joint over two years, especially in cartilage, while hyaluronic acid injections not only avoided this damage but actually showed reduced joint deterioration post-injection,” she said. “Corticosteroids are known to reduce inflammation but also impair the repair mechanisms of cartilage and can inhibit matrix synthesis.”

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