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Transforming Alzheimer’s Care Through the Power of Music Therapy

Music Therapy

Alzheimer’s disease is a condition that affects millions of people worldwide, impacting their memory, emotions, and ability to communicate. For those living with this progressive disease, daily life can become increasingly difficult as cognitive functions decline. While medication and clinical trials play a crucial role in treatment, alternative therapies such as music therapy are gaining recognition for their ability to improve quality of life.

Music therapy is more than just a way to enjoy melodies; it’s a scientifically-backed method that helps Alzheimer’s patients unlock memories, enhance communication, and improve emotional well-being. Alongside advancements in traditional research, music therapy offers a holistic approach that resonates with patients and their families. Let’s explore the incredible connection between music and the brain, and how this therapy is transforming lives. 

The Link Between Music and Memory

Music has a unique ability to access parts of the brain that remain relatively unaffected by Alzheimer’s disease, even in its later stages. Unlike spoken language, music activates neural pathways that are deeply tied to emotion and memory. This is why a familiar song can bring back long-lost memories, allowing patients to recall details they might otherwise struggle to access. For example, a person who cannot remember their own name might suddenly sing along to a childhood tune with remarkable accuracy.

Studies have shown that music therapy can trigger autobiographical memories, helping Alzheimer’s patients reconnect with their past. These findings align with efforts like Lilly clinical trials on Alzheimer’s disease, which aim to address the root causes of memory loss. While clinical trials focus on slowing or stopping cognitive decline, music therapy provides a complementary way to tap into preserved memories, offering moments of joy and clarity for patients and their families.

Music Therapy and Emotional Well-Being

Living with Alzheimer’s often comes with a range of emotional challenges, including anxiety, depression, and feelings of isolation. Music therapy has been shown to significantly improve mood and reduce these negative emotions. Listening to music can release dopamine, a chemical in the brain associated with happiness, while calming rhythms help lower stress levels. This can be particularly helpful during moments of agitation, which are common among Alzheimer’s patients.

Real-life examples demonstrate the power of music in uplifting spirits. One caregiver shared how her mother, who rarely spoke due to Alzheimer’s, would light up and smile whenever her favorite song played. Such experiences highlight how music therapy not only benefits patients but also strengthens the emotional bond between them and their caregivers. These emotional improvements align with ongoing efforts in clinical studies which aim to enhance the overall well-being of those affected by Alzheimer’s. 

Enhancing Communication Through Music

As Alzheimer’s progresses, patients often lose the ability to communicate effectively, leading to frustration and disconnection from loved ones. Music therapy provides a powerful way to bridge this communication gap. Through singing, clapping, or even humming along to a tune, patients can express themselves without relying on words. Music becomes a universal language that helps patients share their emotions and engage with others.

One example comes from a music therapist who worked with a patient who had not spoken in months. By playing songs the patient loved, the therapist was able to elicit responses through facial expressions, hand movements, and eventually humming. Over time, the patient’s engagement improved, creating meaningful moments of connection. These small victories mirror the broader goals of initiatives which strive to improve the quality of life for Alzheimer’s patients and their families. 

Scientific Studies Supporting Music Therapy

The effectiveness of music therapy is not just anecdotal—it is supported by a growing body of scientific research. Studies show that music therapy can reduce symptoms of Alzheimer’s, such as agitation and confusion, while also improving cognitive functions like attention and memory. Brain imaging scans reveal that music activates multiple areas of the brain, even in patients with significant neural damage.

Researchers have also found that personalized music therapy is particularly effective. Tailoring playlists to a patient’s preferences and life experiences maximizes the impact of the therapy. For example, a study found that patients who listened to familiar songs from their youth showed increased engagement and a sense of comfort. These findings complement advancements in clinical research, such as those spearheaded by Lilly Alzheimer’s research clinical trials, which focus on developing comprehensive treatment strategies for Alzheimer’s disease.

Implementing Music Therapy at Home or in Care Facilities

Music therapy is not limited to specialized programs—it can be implemented at home or in care facilities with relative ease. Caregivers can create playlists of their loved one’s favorite songs, focusing on music that holds personal significance. Incorporating music into daily routines, such as during meals or bedtime, can also provide structure and reduce stress for Alzheimer’s patients.

In care facilities, group music therapy sessions are becoming increasingly popular. These sessions encourage social interaction while stimulating cognitive and emotional responses. Some facilities even partner with researchers to measure the long-term benefits of music therapy on patient outcomes. Whether at home or in a professional setting, music therapy offers a versatile and effective way to support Alzheimer’s patients in their journey.

Final Thoughts

Music therapy is a remarkable tool for supporting Alzheimer’s patients, offering a way to unlock memories, improve mood, and enhance communication. It provides hope and comfort not just for those living with the disease but also for their families and caregivers. By stimulating parts of the brain that remain intact, music creates moments of joy and connection, even in the face of memory loss and cognitive decline.

As we continue to explore innovative approaches like music therapy, it’s important to recognize the role of clinical research in addressing Alzheimer’s on a broader scale. Research erelated initiatives are crucial for developing new treatments and understanding the disease’s complexities. Together, traditional research and alternative therapies create a comprehensive approach to improving the lives of those affected by Alzheimer’s.

For caregivers and loved ones, incorporating music therapy into daily routines can be a simple yet effective way to make a difference. Whether it’s through creating personalized playlists, singing familiar songs, or engaging in rhythmic activities, music has the power to heal and transform. By combining the best of science and creativity, we can continue to bring light into the lives of Alzheimer’s patients, one note at a time.

 

Knee Osteoarthritis and How Retraining Gait Alleviates Pain | By Cliff Bleustein, MD, MBA — Global President, CEO, and Director at AposHealth, & Adjunct Professor of Health Economics at NYU Stern School of Business

Knee Osteoarthritis
Cliff Bleustein, MD, MBA — Global President, CEO, and Director at AposHealth, & Adjunct Professor of Health Economics at NYU Stern School of Business

According to recent research, 15% of the global population over the age of 30 is affected by osteoarthritis, or OA, the most common form of arthritis. This same study projects that OA will affect nearly 1 billion people by the year 2050. These statistics show that OA is a pressing medical concern that should be a top priority for medical professionals seeking to improve their patients’ quality of life.

Understanding knee osteoarthritis

Knee osteoarthritis is a medical condition that occurs when the cartilage tissue in the knee wears away. This can cause a number of health issues, including pain, stiffness, swelling, and even more severe consequences in cases where the condition goes untreated. According to studies by the World Health Organization, the knee is the joint most commonly affected by osteoarthritis, with 365 million people worldwide living with osteoarthritis in the knee.

However, the effects of knee osteoarthritis are worse than some minor annoying aches and pains. Knee osteoarthritis can interfere with a person’s ability to do basic activities like walking and climbing stairs, which, in turn, could reduce their activity and exercise levels and have long-term impacts on their health. That’s not to mention the potential mental health consequences of not being able to do activities that one once enjoyed or being excluded from social activities.

Many people think that chronic knee pain is merely a standard part of aging, but that’s simply not the case. If chronic knee pain interferes with one’s ability to go about their regular, daily life, it should signal them that it’s time to seek medical care and treatment for their condition. In some cases, especially if one notices any sudden swelling, it could also be a sign of a more serious condition that needs to be evaluated by a medical professional immediately.

Unfortunately, the typical treatments that are available for knee arthritis are time-consuming at best or invasive or addictive at worst. In milder cases, outpatient physical therapy may be enough to treat the pain, but this requires several visits to a medical office — not to mention a co-pay every time they go. In more severe cases, doctors may suggest prescription painkillers, injections, or even surgery to treat a patient’s pain, but these treatment methods carry with them a risk for complications.

What if there were a way to address some of the most common sources of pain from knee osteoarthritis without surgery, without potentially addictive drugs, and even without the inconvenience of having to go to a physical therapist’s office? The good news is that there is, and it has been proven to significantly benefit patients, allowing them to live their lives less hindered by the obstacle of chronic knee pain: retraining their gait.

How gait retraining can help relieve knee pain

Gait is how a person walks, and even slight changes in walking patterns can put extra stress on the knees, back, hips, and neck — creating a vicious cycle of pain. Addressing gait doesn’t just relieve symptoms; it corrects the root cause of pain, providing immediate relief and lasting improvements.

One innovative way to treat knee pain is through Apos, an FDA-cleared precision medicine solution. Apos uses a personalized foot-worn medical device and a treatment program that simplifies the complex science of gait retraining and combines advanced biomechanics and neuromuscular retraining. While all the patient needs to do is wear the footworn device, the science behind the scenes is fascinating. The device redistributes pressure away from painful areas and introduces subtle micro-instability, encouraging the body to naturally retrain its muscles and nervous system. This non-invasive, drug-free approach changes how patients move, reducing pain and improving function.

Clinical studies have shown that 89% of patients avoid or delay knee replacement surgery — even six years after treatment. Further studies have shown that Apos significantly improves patients’ quality of life and reduces pain while lowering their reliance on medication. With just one hour of use per day, patients can retrain their gait without disrupting their daily routines.

Best of all, Apos is convenient and affordable, with many insurance plans covering the treatment. It can be done entirely from home, making it an accessible alternative to surgery or other invasive treatments. For those suffering from knee osteoarthritis, gait retraining with Apos offers a way to walk better, live better, and reclaim an active lifestyle.

— Dr. Clifford Bleustein is the Global President and CEO of AposHealth. Prior to AposHealth, Dr. Bleustein was President and CEO of Computer Task Group (NASDAQ: CTG), where he managed >3400 people globally and >$340M in revenue across healthcare, technology services, energy, and financial services with operations in North America, Western Europe, and India. Dr. Bleustein went to CTG from Dell, where he had several roles, rising to become the Chief Medical Officer and Global Healthcare Solutions Leader with P&L responsibility for Healthcare & Life Sciences Solutions globally. Dr. Bleustein also had a successful period as a consultant at PwC, rising to Director with a diverse experience of projects including interim executive director of outpatient services, business strategy, international “biocluster” development, mergers & acquisitions, healthcare operations, physician alignment, governance, and resource optimization. He also has on-the-ground experience in the UK, Ireland, India, South Africa, and China, with assessments in the Middle East/Asia.

References:

  1. Benn, R., Rawson, L., & Phillips, A. (2023). “Utilising a non-surgical intervention in the knee osteoarthritis care pathway: A 6-year retrospective audit on NHS patients. Therapeutic Advances in Musculoskeletal Disease.” https://doi.org/10.1177/1759720X231187190.
  2. Reichenbach S., Felson D.T., Hincapi C.A., Heldner S., Bütikofer L., Lenz A., da Costa B.R., Bonel H.M., Jones R.K., Hawker G.A., Jüni P. “Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis.” The BIOTOK Randomized Clinical Trial. JAMA 2020;323(18):1802-1812. https://pubmed.ncbi.nlm.nih.gov/32396180/

Josh Mark, Shirley Shema-Shiratzky, Joel Sommer, Tim Nolan, Ganit Segal. “Reduction in Healthcare Resource Utilization Following Treatment With a Home-Based Footworn Device in Patients With Knee Osteoarthritis: A Retrospective Claims Analysis.” J Health Econ Outcomes Res. 2024 May 16;11(1):134-140. doi: 10.36469/001c.117155.eCollection 2024. https://pubmed.ncbi.nlm.nih.gov/38765914/.

Caranx Medical Announces FDA Submission of TAVIPILOT Soft: the World’s first AI Software for Real-time Intra-operative Guidance of Transcatheter Heart Valve Implantation

Caranx Medical (“Caranx”), a French medical device company specializing in the development of an autonomous robot to democratize access to Transcatheter Aortic Valve Implantation (TAVI), a lifesaving procedure, today announced FDA submission of the world first AI Software for real-time intra-operative guidance of transcatheter heart valve implantation.

The FDA submission marks a significant milestone of Caranx strategy towards planned market introduction of TAVIPILOT Soft by end of 2025.

“The team at Caranx has achieved an important milestone in the submission to the Food and Drug Administration, FDA. This extremely promising step paves the way to early commercialization of the TAVIPILOT Soft by end 2025. I am very excited about the real-time guidance of TAVI/TAVR, a key to accurate and precise positioning of the heart valve as well as the promotion of potentially more predictable and controlled valve deployment” says CEO of Caranx Jorgen Hansen

“Allowing a broader number of cardiologists, surgeons and interventional cardiology centers to perform complex procedures, such as TAVI, the Caranx AI-driven software and autonomous robot is at the heart of our mission of entrepreneurs and business builders to save lives and revolutionize medicine” says Philippe Pouletty, MD, founder of Caranx and CEO of Truffle Capital

“This first release of our TAVIPILOT software marks an important step toward AI-augmented procedures. Our software is designed to be user-friendly, ensuring that cardiologists and surgeons can integrate it seamlessly into their usual practice. TAVIPILOT Soft allows clinicians to position a prosthetic valve easily and with high precision, ensuring that more patients could benefit from a high quality of care.” says Caranx Medical co-founder and CTO Pierre Berthet-Rayne

“TAVIPILOT soft is a breakthrough for TAVI procedures, providing millimetric precision using augmented reality. Clinicians use precise preoperative images (CT-scan) for the planning of TAVI. However, during the procedure, they rely only on fluoroscopy, which shows the anatomy indirectly (requiring contrast injection) and transiently. Accurately positioning the valve requires long training and experience. Our TAVIPILOT Soft identifies key heart anatomical features for precise valve placement and is expected to transform TAVI procedures for patients and clinicians” says Caranx Medical co-founder and CMO Eric Sejor.

The TAVI procedure was introduced app. 20 years ago, and still critical challenges and long learning curves are faced by cardiologists and surgeons during these procedures for a precise and accurate delivery of the heart valve. While 300.000 TAVI procedures are performed annually in the USA and EU, 1.700.000 patients are in need of a TAVI procedure. According to Frost and Sullivan, the current TAVI market is $8Bn growing double digits annually. Caranx products could broadly increase the number of patients benefiting from TAVI.

TAVIPILOT Soft is an easy-to-use, AI-driven intra-operative software which tracks real-time anatomical and instrument landmarks. It enables precise and accurate heart valve positioning and delivery. TAVIPILOT Soft is expected to be a revolution for the transcatheter replacement of aortic valves, which is limited today because it is reserved for the most experienced cardiologists and centers. TAVIPILOT Soft is compatible with all cardiac Imaging Systems and will be compatible with principal TAVI heart valves on the market.

“At Caranx Medical, our vision extends to developing our Artificial Intelligence Platform, currently containing more than 5000 annotated multimodality images of CT, Fluoroscopy, Echo, data, etc. used to feed our AI algorithms and to revolutionize other cardiovascular indications, such as mitral and tricuspid valve replacements, reshaping the landscape of interventional medicine” says CEO of Caranx, Jorgen HANSEN

Designing a Narcolepsy-Friendly Home to Boost Sleep Quality and Wellness

Designing a Narcolepsy-Friendly Home to Boost Sleep Quality and Wellness

Living with narcolepsy can be challenging, especially since it affects not only the body’s ability to stay awake but also the overall quality of life. People with narcolepsy experience excessive daytime sleepiness, sleep paralysis, and even sudden loss of muscle tone, known as cataplexy. These symptoms can disrupt daily routines, work, and social life. Creating a narcolepsy-friendly home environment can help manage these symptoms, allowing people with narcolepsy to have a more restful and productive life. The goal is to design a space that promotes relaxation, reduces distractions, and enhances sleep, which can contribute to better management of narcolepsy.

As research into narcolepsy progresses, it’s important to recognize that the home environment plays a significant role in managing this condition. While ongoing studies, including a narcolepsy clinical trial, aim to find more effective treatments, making your home a peaceful and organized space can help alleviate some of the challenges of living with narcolepsy. By integrating practical strategies for creating a restful living space, people with narcolepsy can improve their sleep quality and overall well-being.

Creating a Comfortable Sleep Environment

A comfortable sleep environment is essential for anyone living with narcolepsy, but it’s particularly crucial for people who experience daytime sleepiness and unpredictable sleep patterns. The first step in creating a narcolepsy-friendly home is ensuring that the sleep area is quiet, dark, and cool. Bright lights and loud noises can interfere with sleep, so consider using blackout curtains or sleep masks to block out light. Additionally, noise can be a significant disturbance, so using a white noise machine or earplugs can help create a more peaceful space.

In terms of the bed, it’s vital to invest in a mattress and pillows that provide proper support and comfort. A well-suited bed can significantly impact the quality of sleep, helping to reduce fatigue. People with narcolepsy often need to rest throughout the day, and a comfortable sleep environment can facilitate these much-needed naps. Research into narcolepsy, particularly in Takeda narcolepsy clinical trials, continues to explore how treatments can improve sleep, but having a dedicated, comfortable sleep space can complement these efforts by ensuring people with narcolepsy get restful sleep when they need it most.

Reducing Noise and Light Distractions

For narcolepsy patients, reducing noise and light distractions is a vital part of improving their sleep quality. Sleep disorders can be aggravated by bright light or disruptive sounds, both of which interfere with the body’s ability to follow natural sleep-wake cycles. Consider adjusting your home lighting to suit your needs, using dimmable lights, or installing circadian lighting systems that adjust throughout the day to support a consistent sleep schedule. For nighttime, it’s helpful to have a system that can automatically reduce light to a minimal level when preparing to sleep.

Additionally, controlling noise in the home is essential. Noise-canceling headphones or soundproofing materials around the house can significantly reduce distractions. For those who prefer complete quiet, incorporating soft, absorbent materials like rugs, curtains, or foam panels can help muffle sounds. When the house is quieter, it allows for a more restful atmosphere that supports better sleep, even during the day. Since clinical trials for narcolepsy treatments are also considering ways to improve sleep by targeting underlying causes, creating a calm home environment will help manage symptoms, especially as these new treatments are developed.

Organizing the Home for Restful Living

A cluttered home can lead to unnecessary stress, which can exacerbate narcolepsy symptoms like fatigue and difficulty concentrating. For a narcolepsy-friendly home, it’s important to organize spaces in a way that reduces visual distractions and promotes a sense of calm. Start by decluttering common areas, such as the living room and kitchen, and organizing spaces so everything has its place. When your environment feels organized and calm, it’s easier to manage daily tasks and reduce the mental load that might otherwise contribute to sleep disruption.

In addition to organizing the living spaces, consider designating specific areas in the home for rest. This could be a quiet corner where you can retreat for short naps or a reading nook that encourages relaxation without distractions. Having designated zones for relaxation is crucial for those with narcolepsy, as it helps prevent sleepiness from interfering with other activities. The more organized your home, the more likely you are to establish routines that can help manage narcolepsy symptoms, even as research into a treatment for narcolepsy continues to progress. 

Adjusting Daily Routines for Better Rest

A consistent daily routine is key to managing narcolepsy. People with narcolepsy often benefit from keeping a regular sleep schedule, even if this includes taking frequent naps. Setting a specific time to go to bed and wake up can help regulate the body’s internal clock. When you sleep and wake at consistent times each day, it becomes easier for your body to adjust to a routine, reducing feelings of sleepiness during the day.

In addition to maintaining a regular sleep schedule, it’s important to pay attention to meal times and activity levels. Avoid heavy meals right before bedtime, as they can make it harder to sleep. Instead, opt for lighter meals in the evening to promote a peaceful night’s rest. Incorporating light physical activity, such as stretching or a short walk, can also improve sleep quality without overexerting the body. As research continues on narcolepsy and its treatments, maintaining a stable routine and balanced lifestyle can support the effectiveness of these treatments, making it easier to manage symptoms.

Implementing Technology and Tools for Support

In today’s world, technology can offer valuable support for those with narcolepsy. Many wearable devices and apps are designed to track sleep patterns and help manage symptoms. These tools can offer real-time insights into sleep quality, allowing users to make adjustments as needed. Additionally, using apps that remind you to take naps or medication can help keep you on track, especially when trying to maintain a regular routine.

Smart home devices can also play a role in managing narcolepsy symptoms. For example, smart lighting systems can adjust automatically to mimic the natural day-night cycle, helping to regulate sleep. Voice assistants can set reminders for scheduled naps or when to take prescribed medication, reducing the mental burden of remembering everything. With the ongoing research into new treatment for narcolepsy, such as promising new therapies being tested in clinical trials, these tools and devices can work in conjunction with treatments to optimize health and well-being.

Final Thoughts

Creating a narcolepsy-friendly home is a vital part of managing this condition and improving the overall quality of life for those affected. Adjustments to the home environment, such as ensuring a comfortable, quiet sleep area, reducing light and noise distractions, and organizing spaces to minimize stress, can significantly enhance rest. Having a calm, well-structured living environment helps narcolepsy patients maintain better sleep patterns, reducing the disruptions caused by the condition. Furthermore, maintaining a consistent daily routine and utilizing tools to track sleep can empower individuals to better manage their symptoms.

While ongoing research into narcolepsy continues to progress, creating a supportive home environment complements these advancements. A peaceful and organized space allows individuals with narcolepsy to rest and recuperate effectively, which is essential for their well-being. By fostering an environment that promotes relaxation and minimizing the challenges caused by narcolepsy, those living with the condition can enhance their sleep and overall quality of life. With the right combination of medical treatment and home adjustments, managing narcolepsy becomes a more achievable goal, leading to a more restful and fulfilling life.

Striking the Right Balance: Managing Screen Time for Kids’ Health and Development

Striking the Right Balance: Managing Screen Time for Kids' Health and Development

Digital devices have become a key part of everyday life, with smartphones, tablets, and computers playing a significant role in children’s routines. Whether for schoolwork, entertainment, or socializing, screens are now an essential tool for kids. While they provide benefits, such as access to educational resources and creative outlets, there are growing concerns about how excessive screen time might impact children’s physical, cognitive, and emotional health. As parents, finding the right balance between screen time and other activities is crucial to help children maintain healthy habits and strong developmental foundations.

Navigating this balance is a challenge for many families. While technology offers valuable learning experiences, it’s equally important for children to engage in physical play, face-to-face interactions, and quiet time away from screens. Overuse of digital devices can contribute to health problems like eye strain, poor posture, and sedentary behavior, which can lead to conditions such as obesity and sleep difficulties. Socially, too much screen time can hinder the development of important interpersonal skills. Setting limits on screen time while encouraging other enriching activities is key to ensuring children grow up with a well-rounded and healthy lifestyle.

Understanding the Impact of Screen Time on Physical Health

One of the most significant concerns regarding screen time is its effect on children’s physical health. Prolonged use of digital devices can lead to poor posture, eye strain, and an increased risk of obesity due to reduced physical activity. When kids spend long hours sitting in front of a screen, they miss out on opportunities for movement and play, which are essential for developing strong muscles and bones. Research has also shown that excessive screen time can disrupt sleep patterns, making it harder for children to fall asleep at night, further contributing to physical health problems.

To combat these issues, parents can encourage their children to take frequent breaks from screens and engage in physical activity. Whether it’s a walk in the park, playing outside with friends, or doing an active game at home, getting kids moving is key to balancing screen time. Additionally, parents can consult with a pediatrician near me for personalized advice on how much screen time is appropriate based on their child’s age and health needs. Pediatricians can offer guidance on the ideal amount of daily screen use and suggest ways to maintain healthy habits as children grow. 

Cognitive Development and Screen Time: Pros and Cons

Screen time’s impact on children’s cognitive development is a complex topic. On the positive side, certain digital content, such as educational apps and videos, can support learning and help develop cognitive skills. For example, interactive games can enhance problem-solving abilities, boost memory, and improve coordination. With the right content, screens can be used as a valuable tool to supplement classroom learning and teach kids new concepts in fun and engaging ways.

However, the negative effects of too much screen time on cognitive development can’t be ignored. Excessive screen use has been linked to reduced attention spans, difficulty focusing, and lower academic performance in some children. Long hours of passive screen time, such as watching TV or playing video games, can hinder a child’s ability to concentrate on more demanding tasks, like reading or homework. It’s important for parents to set clear limits on screen time and encourage a variety of activities that stimulate cognitive development, such as reading, puzzles, and creative play. If you have concerns about how screen time might be affecting your child’s learning abilities, consulting with a pediatrician may help rule out underlying conditions that could impact cognitive function.

The Emotional Impact of Screen Time on Kids

Screen time doesn’t just affect children’s physical and cognitive health – it also significantly impacts their emotional well-being. Studies have shown that excessive screen time, particularly on social media, can contribute to feelings of anxiety, depression, and social isolation in children. Platforms expose kids to unrealistic expectations, cyberbullying, and constant comparisons, which can damage their self-esteem. Moreover, too much screen time reduces opportunities for face-to-face interactions, which are essential for developing strong emotional bonds with family and friends.

To safeguard children from these emotional risks, parents should encourage balance and set clear boundaries for screen use. For example, avoiding screens during family meals or before bed promotes more in-person interaction and healthier sleep patterns. It’s also important to monitor the content children consume, ensuring it aligns with their age and emotional development. If you notice signs of emotional distress, it’s wise to reach out to an allergist near me for advice, especially if there are concerns about underlying conditions affecting emotional health. Allergists can help address any health concerns that may impact a child’s well-being while providing strategies for balancing screen time with overall health.

Practical Tips for Setting Healthy Screen Time Boundaries

Setting healthy screen time boundaries doesn’t have to be difficult, but it does require consistency and planning. One effective approach is to create a family screen time schedule that includes designated times for educational screen use, entertainment, and offline activities. For instance, setting a limit on recreational screen time to an hour or two per day can help children stay engaged in other activities. Having clear screen-free times, like during meals or right before bed, encourages better family interactions and sleep habits.

Additionally, parents can establish tech-free zones in the home, such as the dining room or bedrooms, to create a space for quality time and rest without distractions. It’s also essential to model healthy screen habits. Children often imitate the behavior they see in their parents, so setting an example of limited screen use can be a powerful tool in helping kids understand the importance of balance. Regular check-ins with a pediatrician can also help parents determine whether their child’s screen time is aligned with their developmental needs. A pediatrician can provide expert advice on managing screen time based on your child’s health and behavior.

Final Thoughts

Finding the right balance between screen time and other aspects of life is crucial for promoting healthy development in children. While digital devices offer educational opportunities and entertainment, excessive screen time can lead to physical, cognitive, and emotional challenges. Parents must be proactive in setting limits on screen time, encouraging physical activity, and fostering real-world connections. By consulting with healthcare professionals for specific health concerns, parents can ensure their children are developing in a healthy and well-rounded way. By creating a balanced routine and prioritizing activities that promote overall well-being, parents can help their kids grow into healthy, happy individuals.

6 Month Real World Experience Study Confirms Efficacy and Safety of SING IMT ® for Late-Stage Age-Related Macular Degeneration

6 Month Real World Experience Study Confirms Efficacy and Safety of SING IMT ® for Late-Stage Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a progressive retinal disorder affecting the macula, leading to central vision loss, primarily in older adults. Advanced AMD affects approximately 1% of individuals in developed countries and is divided into two forms: wet (neovascular) and dry (atrophic). While anti-VEGF therapies provide treatment for wet AMD, no therapies are currently available to restore vision in the 80–90% of patients with dry AMD, representing a significant unmet medical need.

To address this gap, a promising option available in CE Mark-referenced countries and under investigation in the United States is the Smaller-Incision New-Generation Implantable Miniature Telescope, or SING IMT®. This innovative intraocular device, designed for individuals with late-stage AMD, has shown positive intermediate-term results in improving both visual and safety outcomes, as recently reported by Samsara Vision.

Real-World Validation: Six-Month Study Outcomes
Published in the journal Heliyon, the new study found that SING IMT improved both distance and near vision — while exhibiting minimal effects on corneal endothelial cell density and a favorable safety profile.

Six months post-implantation (n=35), 97.1 percent of eyes achieved at least a one-line improvement in best-corrected distance visual acuity (BCDVA), while 68.6 percent and 51.4 percent of eyes achieved two- and three-line gains, respectively. The mean ± standard deviation (SD) change in BCDVA from baseline was −0.29 ± 0.142. Near visual acuity improved substantially, with 97.1% of patients able to read at near distance compared to 28.6% at baseline. Corrected near visual acuity improved by an average of three lines, underscoring the device’s impact on functional vision, which is strongly linked to vision-related quality of life. From a safety perspective, corneal edema persisting beyond 30 days was the most common complication, affecting 22.9% of patients. All cases were resolved with topical medications. Importantly, endothelial cell loss observed at six months was minimal, alleviating concerns about long-term safety. Compared to earlier versions of the device and standard cataract surgery, SING IMT demonstrated reduced endothelial cell loss, highlighting advancements in surgical design and safety outcomes. These findings support the efficacy and safety of the SING IMT as a therapeutic option for late-stage AMD.

The Study Design
This retrospective study included 35 patients aged 55 or older with bilateral late-stage AMD and cataract in the study eye. Participants had CDVA in the range of 20/80–20/800 without other retinal pathologies and good peripheral vision in the fellow eye. The study was conducted at two different sites. The SING IMT was implanted using standard cataract surgery techniques with a continuous manual circular anterior capsulorhexis. The foldable telescope devise, preloaded in a delivery system, was inserted through a 7.5–8 mm limbal incision at the 12 o’clock position and positioned in the capsular bag. The incision was sutured, and an in few cases iridectomy was performed.

Six weeks post-surgery, patients underwent a mandatory rehabilitation program consisting of approximately eight 90-minute sessions over six months. The program included exercises to improve visual skills such as reading, tracking, visual-motor integration, and mobility, aiming to optimize the collaboration between the implanted eye and the fellow eye.

The Science behind SING IMT
The Smaller-Incision New-Generation Implantable Miniature Telescope (SING IMT) operates on well-established Galilean-like optical principles to address central vision loss in late-stage AMD. In a healthy eye, light diverging from a real object, such as a book, is focused by the cornea and crystalline lens onto the retina, forming an image. In late-stage AMD, central retinal damage prevents the formation of a clear image in the central field of vision. The SING IMT replaces the crystalline lens and utilizes its optical system, comprising advanced micro-optics that magnify the central field of view by approximately 2.7 times. This magnification effectively reduces the relative size of the central scotoma (blind spot), enabling the patient to perceive an enlarged image that “bypasses” the damaged central retina. As a result, individuals can regain the ability to perform visually demanding tasks, such as recognizing faces, reading, and watching television.

The device is implanted monocularly, preserving the peripheral vision of the untreated eye, which is essential for spatial orientation and balance. Post-implantation visual rehabilitation plays a critical role in optimizing outcomes, as it helps patients adapt to the magnified central image and integrate it with peripheral vision. To date, the SING IMT has been implanted in over 400 patients across 19 CE-referenced countries, with initial clinical results demonstrating its potential as a viable intervention for late-stage AMD.

The Conclusion
The SING IMT represents a significant advancement in addressing the unmet needs of patients with late-stage AMD, offering measurable improvements in both near and distance vision. By enabling patients to regain functional vision, such as reading, recognizing faces, and navigating their environment, the device demonstrates its potential to significantly enhance quality of life. These outcomes highlight the critical role of ongoing collaboration between surgeons, patients, and rehabilitation specialists in optimizing visual outcomes. Continued research and real-world validation will further establish the SING IMT as a transformative intervention for late-stage AMD.

Editor’s Note Dr. Faustino Vidal-Aroca is Vice President, Research and Development at Samsara Vision. With over 15 years of global experience in medical affairs, clinical operations, and scientific innovation, Dr. Vidal-Aroca brings a proven track record of leading impactful research and advancing patient care in ophthalmology. 

A prolific contributor to high-impact peer-reviewed publications, Dr. Vidal-Aroca holds a PhD in Molecular Biology and Biochemistry, completed jointly at the University of Madrid and the University of Milan, and has been recognized with prestigious honors, including a Marie Curie Fellowship from the European Commission. He also has an Executive MBA from SDA Bocconi. 

Promising Results Emerge in Early Access Care Trials for the Terminally Ill

Early Access Care

Recent advances in early access care programs for terminally ill patients have shown encouraging outcomes, suggesting a potential paradigm shift in end-of-life treatment approaches. These innovative programs, which provide experimental treatments to patients who have exhausted standard therapeutic options, are demonstrating positive impacts on both survival rates and quality of life metrics.

The concept of early access care, also known as expanded access or compassionate use, has evolved significantly over the past decade. Traditional approaches to terminal illness often focused primarily on palliative care, but emerging research indicates that carefully managed experimental treatments can offer new hope without compromising patient comfort or dignity.

Dr. Sarah Chen, lead researcher at the Metropolitan Institute for Advanced Medical Studies, explains the significance of recent findings: “We’re seeing a remarkable shift in how we approach terminal illness. By providing carefully selected patients with access to experimental treatments earlier in their disease progression, we’re observing extended survival periods and, in some cases, unexpected improvements in disease markers.”

A comprehensive study conducted across multiple research centers has documented promising results in patients with advanced-stage cancers. The study, which included 2,500 participants across 15 medical centers, showed that patients who received early access to experimental treatments experienced an average 40% longer survival time compared to those who received standard palliative care alone. Perhaps more significantly, 68% of participants reported improved quality of life measures, including reduced pain levels and increased mobility.

The success of these programs can be attributed to several key factors. First, advances in genetic profiling and personalized medicine have enabled medical teams to better match patients with potentially beneficial experimental treatments. Second, improved monitoring systems and rapid response protocols have enhanced the safety profile of these programs. Third, the development of more sophisticated drug delivery systems has reduced the physical burden of experimental treatments on already fragile patients.

Dr. James Morrison, an oncologist at Central State Medical Center, emphasizes the importance of patient selection in these programs: “We’ve learned that careful screening and monitoring are crucial. Not every experimental treatment is suitable for every patient, but when we get the match right, the results can be remarkable. We’re seeing some patients respond in ways we wouldn’t have thought possible even five years ago.”

The financial aspects of early access care programs remain a significant consideration. Insurance companies have traditionally been hesitant to cover experimental treatments, but the growing body of positive evidence is beginning to shift this perspective. Several major insurance providers have initiated pilot programs to cover certain forms of early access care, particularly in cases where conventional treatments have proven ineffective.

Patient advocates have played a crucial role in advancing these programs. Maria Rodriguez, director of the Patient Rights Alliance, notes: “We’ve worked hard to demonstrate that early access care isn’t just about extending life at any cost – it’s about providing hope while maintaining dignity. The quality of life improvements we’re seeing in many patients are just as important as the survival statistics.”

The psychological impact of early access care programs has also emerged as a significant factor. Studies indicate that patients who participate in these programs often experience reduced anxiety and depression compared to those in traditional palliative care. This psychological benefit extends to family members, who report feeling more supported and engaged in their loved ones’ care.

However, medical professionals caution that early access care programs must be approached with realistic expectations. Dr. Chen emphasizes: “While we’re seeing very promising results, it’s important to understand that these are still experimental treatments. Success rates vary, and not every patient will experience dramatic improvements. The key is to maintain honest, open communication with patients and families throughout the process.”

The regulatory landscape surrounding early access care continues to evolve. Recent policy changes have streamlined the approval process for certain experimental treatments, while maintaining crucial safety oversight. This balanced approach has enabled more patients to access potentially beneficial treatments while ensuring appropriate medical supervision and data collection.

Looking ahead, researchers are optimistic about the future of early access care. Ongoing studies are exploring new treatment modalities, including targeted immunotherapies and innovative drug combinations. The integration of artificial intelligence in patient screening and treatment matching is expected to further improve outcomes in coming years.

The medical community is also working to establish more standardized protocols for early access care programs. These efforts aim to ensure consistent quality of care across different institutions while maintaining the flexibility needed to address individual patient needs. International collaboration has become increasingly important, with medical centers sharing data and best practices to accelerate learning and improvement.

Patient education remains a crucial component of successful early access care programs. Medical teams are developing more comprehensive approaches to helping patients and families understand their options and make informed decisions. This includes detailed discussions about potential risks and benefits, as well as realistic expectations for treatment outcomes.

As these programs continue to evolve, the focus remains on balancing hope with realism, innovation with safety, and medical advancement with patient comfort. The emerging data suggests that early access care programs, when properly implemented, can offer valuable options for terminally ill patients while contributing to our broader understanding of disease treatment and management.

The success of these programs represents a significant step forward in our approach to terminal illness, offering new possibilities for patients who previously had limited options. As research continues and treatments advance, the role of early access care is likely to expand, potentially reshaping our understanding of what’s possible in end-of-life care.

Vesilut Peptide: Potential Implications in Biological Systems and Scientific Research

Peptides have garnered significant attention in scientific research for their diverse roles in biological systems. Vesilut peptide has emerged as a promising compound, attracting interest for its unique properties and potential implications across various domains. Although much remains to be explored, Vesilut may hold the key to advancing our understanding of physiological processes and developing innovative approaches to challenges in molecular biology and beyond.

Structural and Functional Insights into Vesilut

Vesilut peptide is characterized by its specific amino acid sequence, which may confer unique interactions within biological systems. Its molecular structure is hypothesized to facilitate selective binding to certain cellular receptors or intracellular targets, suggesting roles in modulating biochemical pathways. This specificity might make Vesilut an intriguing subject for investigations into protein-protein interactions and cellular communication.

The peptide is theorized to interact with cellular components at multiple levels, potentially influencing enzymatic activity, signal transduction, and molecular synthesis. Researchers have speculated that Vesilut’s properties might allow it to influence organ-specific activities, particularly in tissues requiring precise regulatory mechanisms. For instance, its interactions may be linked to cellular maintenance, protein synthesis modulation, or intracellular signaling cascades that contribute to homeostasis.

Vesilut’s Hypothetical Roles in Cellular Processes

One domain of interest is Vesilut’s potential to influence cellular regeneration. It has been hypothesized that these types of peptides might contribute to cellular repair and renewal processes, particularly in tissues with high turnover rates. Such activities might position Vesilut as a key molecule in exploring regenerative science and tissue processes.

Additionally, Vesilut has been hypothesized to impact cellular signaling networks. Signal transduction is fundamental to many physiological processes, and peptides with the potential to modulate these pathways may unlock new research avenues. Investigations purport that Vesilut might interact with specific signaling molecules, possibly regulating pathways involved in growth, differentiation, and metabolic coordination.

Implications for Molecular Biology Research

Studies suggest that in molecular biology, Vesilut may serve as a tool for probing complex biochemical systems. Its hypothesized binding properties might make it suitable for targeting specific proteins or cellular compartments, thereby enabling precise experimental manipulations. For instance, Vesilut might be utilized in studies aiming to delineate protein functions or identify novel therapeutic targets.

Furthermore, the peptide’s potential to stabilize or alter protein conformations might offer insights into structural biology. Research indicates that by modulating protein dynamics, Vesilut might provide a platform for exploring protein folding mechanisms, enzymatic activity modulation, and protein aggregation phenomena.

Theoretical Implications in Physiology

The prospective roles of the Vesilut peptide have been theorized to extend beyond the cellular level to physiology. Hypotheses suggest that the peptide may contribute to the optimization of organ function through its molecular impacts. For example, Vesilut seems to influence processes such as nutrient metabolism, cellular energy dynamics, and waste management within tissues.

Research indicates that Vesilut may be of interest to scientists studying cellular aging processes. Cellular aging is often associated with declining cellular efficiency and increased molecular damage. Vesilut’s properties might even mitigate these impacts, making it a candidate for investigating longevity and age-related physiological changes.

Vesilut in the Context of Biotechnological Innovation

Biotechnology presents another promising avenue for Vesilut implications. Investigations purport that the peptide might be engineered or synthesized for exposure in biosensors, delivery systems, or biomaterials. Its potential to interact selectively with biological targets might make it a valuable component in diagnostic and research technologies.

For instance, Vesilut might be incorporated into nanotechnological tools to investigate targeted exposure or molecular recognition. Peptides like this one are hypothesized to support the precision and efficiency of such processes, which may lead to diagnostic tools and experimental probes.

Potential Impacts on Environmental and Agricultural Sciences

Beyond physiology, Vesilut has been speculated to have relevant implications in environmental and agricultural sciences. Its theorized properties might be harnessed to ‘support plant stress responses, crop resilience, or soil microbial interactions. In environmental monitoring, Vesilut appears to serve as a bioindicator for detecting biochemical changes in ecosystems or as a component in bioremediation strategies.

Future Directions and Speculative Insights

While the Vesilut peptide’s properties remain under active investigation, its potential to impact various scientific domains is compelling. Future research might focus on elucidating its mechanisms of action, refining its implications, and exploring its roles in complex biological systems. Advances in peptide synthesis, structural biology, and computational modeling are likely to accelerate these efforts, offering deeper insights into Vesilut’s potential.

In conclusion, Vesilut peptide represents a fascinating subject for scientific exploration. Its hypothesized properties and potential implications span a wide array of disciplines, from molecular biology and biotechnology to environmental science and physiology. By continuing to investigate this peptide, researchers may unlock new pathways for understanding and manipulating biological systems, contributing to advancements across diverse scientific fields. Researchers interested in the highest-quality research peptides should visit Core Peptides. This article serves educational purposes only.

References

[i] Williams, J. T., & Barnes, L. (2021). Role of peptides in agricultural and environmental science: Challenges and opportunities. Environmental Science and Technology, 55(2), 1217-1229. https://doi.org/10.1021/acs.est.0c04624

[ii] Roberts, A. R., & Foster, C. L. (2020). Peptide-based biosensors and their applications in diagnostics and therapeutic technologies. Nature Biomedical Engineering, 4(6), 515-526. https://doi.org/10.1038/s41551-020-00535-6

[iii] Johnson, E. R., & Wright, J. T. (2019). Peptides as modulators of protein folding and aggregation: Implications for therapeutic development. Trends in Biochemical Sciences, 44(8), 705-717. https://doi.org/10.1016/j.tibs.2019.05.003

[iv] Neve, R. L., & Perez, C. A. (2018). Signaling pathways in cellular regeneration and tissue repair. Journal of Molecular Signaling, 13(3), 54-65. https://doi.org/10.1186/s12900-018-0102-4

[v] Wu, S., & Wang, Q. (2017). Peptide-based modulation of protein-protein interactions in cellular signaling. Biochimica et Biophysica Acta (BBA) – Reviews on Cancer, 1868(1), 39-50. https://doi.org/10.1016/j.bbcan.2016.11.004

 

A Clearer Tomorrow: Healing Your Eyes with LASIK in San Diego

LASIK in San Diego
  1. Seeing Through the Fog: The Fragility of Vision Your eyes—those tiny windows to the world—are both marvels of nature and delicate masterpieces. One stray scratch, a sudden injury, or even years of wear and tear can turn that once-crystal-clear view into something blurred, distorted, or downright frustrating. It’s as though life handed you a smudged lens and left you fumbling to clean it. Thankfully, modern medicine has given us tools to rewrite these stories. One of the brightest stars in this arena? LASIK San Diego is a beacon of hope for anyone tired of peering through the haze of imperfect vision.

Corneal injuries, like potholes on a smooth highway, can make even the simplest tasks—like reading, driving, or enjoying the sunset—challenging. But with the magic of LASIK, those roadblocks don’t have to be permanent.

  1. The Cornea: The Silent Hero of Your Eye Think of your cornea as the unsung hero of your vision. It’s the transparent, outermost layer of your eye, responsible for bending light and helping your brain make sense of the world. It works quietly in the background, a conductor orchestrating the symphony of sight.

But here’s the kicker: the cornea is also vulnerable because it’s exposed. A scratch from a stray fingernail, a mishap during sports, or even a rogue eyelash can cause significant damage. This delicate layer can become cloudy or scarred when injured, distorting how light enters the eye. The result? Blurry vision, sensitivity to light, or worse, a constant reminder that something isn’t quite right.

  1. When Injuries Throw a Wrench in the Works, Corneal injuries don’t affect your ability to see—they alter how you navigate life. Imagine trying to watch a movie through a rain-streaked window or recognizing faces at a party when everything looks like a watercolor painting gone wrong.

Injuries can lead to irregularities in the cornea’s shape or surface. These irregularities might sound like minor inconveniences, but they can wreak havoc on your daily routine. Glasses and contact lenses often fall short when correcting this vision distortion, leaving many feeling out of options.

  1. Enter LASIK: The Game-Changer for Vision Correction. For years, LASIK has been the superhero of the vision world—saving people from the shackles of glasses and contacts. But it’s not about convenience or vanity; LASIK is also a powerful tool for addressing corneal irregularities caused by injuries.

LASIK (short for Laser-Assisted In Situ Keratomileusis, if you’re feeling fancy) reshapes the cornea with the precision that rivals that of a master sculptor working on marble. Using advanced lasers, LASIK can correct irregularities, smooth out imperfections, and restore clarity where it’s been lost. It’s not a treatment—it’s a transformation.

  1. What Problems Can LASIK Solve? LASIK is like a Swiss Army knife for vision correction. It tackles a range of issues, including:
  • Myopia (Nearsightedness): Struggling to see distant objects? LASIK can flatten the cornea to refocus your vision.
  • Hyperopia (Farsightedness): Do you have trouble reading the fine print? LASIK can steepen the cornea, helping you see up close.
  • Astigmatism: This condition, where the cornea is irregular, is often likened to looking through a warped mirror. LASIK can smooth out those irregularities, bringing the world back into focus.
  • Corneal Irregularities from Injuries: Here’s the big one. Whether it’s scarring, thinning, or an uneven surface caused by an accident, LASIK can often step in to restore order where chaos once reigned.
  1. Why San Diego is a Hub for Vision Restoration San Diego isn’t known for its sunny beaches and laid-back vibes—it’s also a hotbed for cutting-edge medical advancements, including vision correction. Clinics specializing in LASIK San Diego combine state-of-the-art technology with experienced surgeons who treat your eyes as their unique masterpieces.

The city’s eye care professionals are well-versed in handling cases of corneal damage, offering personalized solutions that cater to each patient’s specific needs. And let’s face it—recovering in sunny San Diego isn’t a bad deal.

  1. What to Expect from LASIK Surgery The idea of lasers zapping your eyeball might sound like something out of a sci-fi movie, but LASIK is surprisingly quick and painless. Most procedures take less than 15 minutes per eye, and you’ll be back on your feet—figuratively and —within hours.

First, your surgeon creates a tiny flap in the cornea. Then, a laser reshapes the underlying tissue to correct your vision. Finally, the flap is smoothed back into place like the cover of a book, and voila! Your eye begins its healing journey.

Recovery is relatively swift, though you might experience some dryness or sensitivity in the days following the procedure. But for many, the results are nothing short of life-changing.

  1. The Emotional Side of Vision Loss (and Recovery) Let’s talk about the elephant in the room: the emotional toll of living with vision problems. It’s not about struggling to see—it’s about feeling disconnected, vulnerable, or embarrassed. Vision loss can chip away at your confidence, making everyday tasks feel like Herculean feats.

That’s what makes LASIK so unique. It’s not a medical procedure; it’s a second chance. For many, the moment they wake up after surgery and see the world is magical. It’s a reminder that life is meant to be seen in all its vivid, high-definition glory.

  1. Is LASIK Right for You? Not everyone is a candidate for LASIK, and that’s okay. Factors like the thickness of your cornea, the degree of damage, and eye health all play a role in determining whether the procedure is a good fit.

That’s why a thorough consultation is crucial. San Diego’s LASIK specialists take the time to test your unique situation, ensuring that you’re not a number on a chart but a person with specific needs and concerns.

  1. Wrapping It Up: A New View on Life Your eyes are more than organs—they’re storytellers, capturing the world’s beauty and sharing it with your soul. And when injury or vision problems threaten to dim that light, it’s reassuring to know that options like LASIK San Diego https://drmotwani.com/ exist to bring it back.

Whether you’re dealing with corneal damage from an accident or struggling with long-standing vision issues, LASIK offers a pathway to clarity, confidence, and a brighter tomorrow. Because life is too short to live in a blur, why not take the first step toward seeing it again?

NFL Alumni Joel Dreessen and Le-Lo Lang Team Up With HeartFlow and Boone Heart Institute to Launch GAMEFILM Registry to Assess Heart Disease Risks in Retired Football Players

HeartFlow, Inc., the global leader in non-invasive artificial intelligence (AI) heart care solutions, and Boone Heart Institute, a Denver area leader in preventive cardiovascular care, today announced the launch of the GAMEFILM Registry, a post-market, data collection registry designed to define cardiac risk in retired National Football League (NFL) players.

Retired NFL players Joel Dreessen and Le-Lo Lang will be among the first individuals in the registry to receive a coronary artery disease (CAD) assessment with HeartFlow’s AI-driven technology. Dreessen played tight end for eight seasons with the Denver Broncos, Houston Texans, and New York Jets, while Lang played four seasons as a cornerback for the Broncos.

The GAMEFILM Registry will enroll approximately 120 NFL alumni. The Registry will leverage coronary computed tomography angiography (CCTA) imaging and insights from the HeartFlow ONE platform (HeartFlow FFRCT and Plaque Analysis) to collect observational data with the goal of better understanding CAD prevalence, risk factors, severity, and treatment protocols among retired athletes. The first site for the GAMEFILM Registry is now enrolling at the Boone Heart Institute in Colorado, representing a significant step forward in understanding the cardiovascular health of retired professional athletes, a population that faces distinct risks due to the physical demands of their careers.

“While up to one in three retired professional football players die of cardiovascular disease, much remains unknown about the prevalence of risk factors and severity of disease among these former high-performing athletes,” said Jeffrey L. Boone, M.D., Founder and Medical Director of the Boone Heart Institute. “By offering CCTA combined with HeartFlow FFRCT and Plaque Analysis, we’ll generate real-world data in the GAMEFILM Registry that will provide deeper insights into the unique cardiovascular challenges facing former professional football players, which will help us form protocols that meet their unique needs. The findings will help pave the way for actionable strategies for prevention, earlier detection, and improved care within this population.”

By utilizing HeartFlow’s FDA-cleared FFRCT and Plaque Analysis technologies, the study will inform development of prevention and treatment strategies tailored to former NFL players and similar populations worldwide. HeartFlow’s AI-driven technologies have helped healthcare providers diagnose CAD and guide treatment decisions for more than 400,000 patients.

“More than 50% of people who die from coronary artery disease have no prior diagnosis or testing, underscoring the importance of getting a clear picture of your heart health to understand and try to prevent heart attacks and death,” said Joel Dreessen, retired Denver Broncos tight end. “Participating in the GAMEFILM Registry is an important step toward better understanding our heart health and addressing the unique cardiovascular risks we face as retired professional athletes.”

“Better, more specific insights, while certainly beneficial for my health, could also ultimately help protect the heart health of generations to come,” added Le-Lo Lang, retired Denver Broncos cornerback. “I’m proud to be partnering with Dr. Boone and HeartFlow to encourage all retired players to take advantage of this helpful technology and get a personalized 3D model of their cardiovascular health.”

Cardiovascular diseases are the leading cause of death in the United States and worldwide. Despite significant advancements in diagnostic pathways, many major adverse cardiovascular events (MACE), such as heart attacks, occur in patients without symptoms. Four out of five heart attacks and strokes are preventable with lifestyle and nutrition changes if patients at high risk are identified early.1 Understanding plaque burden – where plaque is located in the coronary arteries, the amount of plaque, and the type of plaque – is one of the best ways for physicians to identify patients at high risk of death from a heart attack.2

“We are proud to initiate the GAMEFILM Registry to help identify at-risk patients using HeartFlow’s CAD diagnosis and management technology,” said John Farquhar, President and Chief Executive Officer of HeartFlow, and an NFL alumnus. “I’m optimistic that through this effort we can help other NFL alumni gain valuable insights into their heart health.”

By combining the advanced imaging capabilities of CCTA with the HeartFlow ONE Platform, clinicians can better understand functional information about each coronary artery and blockage and quantify and characterize plaque burden in coronary arteries, enabling more precise risk assessment and targeted medical interventions.

HeartFlow is dedicated to defeating heart disease through partnering with physicians to generate robust, high-quality clinical evidence. HeartFlow has been adopted by more than 1,300 institutions globally and continues to strengthen its commercial presence to make this cutting-edge solution more widely available to an increasingly diverse patient population worldwide.