CLINICAL TRIALS, STUDIES, REGISTRIES, DATA

Vidofludimus Calcium's Activation of Nurr1 reduces neuronal loss and injury directly and Indirectly by decreasing microglial activations in preclinical models.

The Audiogene trial is designed to evaluate the safety, tolerability and efficacy of intra-cochlear injection of SENS-501 for the treatment of OTOF gene-mediated hearing loss in paediatric patients aged between 6 and 31 months at the time of gene therapy treatment. By targeting the first years of life, when brain plasticity is at its peak, the chances of these young children with pre-linguistic hearing loss of acquiring normal speech and language are maximised. The trial is comprised of two cohorts of two doses followed by an expansion cohort at the selected dose.

This article gives an overview of the new clinical trial regulations, explaining how key changes will impact clinical research, and how this new accelerated access to clinical innovation will ultimately impact patient care.

"Neuropathy is incredibly common among the aging population, regardless of disease states. There is currently no known cure for neuropathy, and most treatments address acute symptoms with no lasting impact," says Dr. Ramona von Leden, VP of Research and Clinical Affairs for NeuFit. "NeuFit's specialized approach to rehab focuses on supporting the function of the nervous system, and we are seeing remarkable results on patients with neuropathy."

Dr. Joel Braunstein, CEO of C2N Diagnostics, says, “This research increases the growing body of evidence that demonstrates high clinical utility with blood biomarkers, which is bringing important advancements to the field. Too often, patients face a complex and delayed diagnostic journey when dealing with new cognitive concerns. High-performance testing with our PrecivityAD2 blood test has the potential to provide clarity and shorten that diagnostic journey, while significantly elevating healthcare quality.”

Interactive Response Technology (IRT) helps clinical trial sites and sponsors manage both participant randomization and trial supply management (RTSM). What was once a manual,...

The GAMEFILM Registry will enroll approximately 120 NFL alumni. The Registry will leverage coronary computed tomography angiography (CCTA) imaging and insights from the HeartFlow ONE platform (HeartFlow FFRCT and Plaque Analysis) to collect observational data with the goal of better understanding CAD prevalence, risk factors, severity, and treatment protocols among retired athletes.

“We are delighted to have treated the first patients – this is a significant milestone in our clinical trial and our mission to develop curative treatments for critically ill cancer patients. We have an outstanding trial team and look forward to the upcoming results,” says Samuel Svensson, CEO of Neogap Therapeutics.

The focal point of the study is the growing role of machine learning in wearables. Peer-reviewed research from PubMed, MDPI, ScienceDirect, and other leading sources for scientific and medical research proves that monitoring vital signs, such as heart rate, can support the early detection of health risks and potentially reduce reliance on traditional in-person medical examinations.