Dr. Hui Zhou, Senior Vice President of Innovent, stated: “IBI363, as a first-in-class molecule, represents Innovent’s continuous innovation and advancement in the immunotherapy field. Starting from molecular design, the unique approach of α bias with β and γ attenuated were creatively adopted, which greatly improved the therapeutic window of IL-2. Meanwhile, through the specific traction of PD-1, tumor-specific T cells expressing both PD-1 and CD25 can be selectively stimulated and amplified, thus exerting anti-tumor effects. IBI363 has demonstrated excellent druggability with antibody-like pharmacokinetics (IgG-like PK) and low immunogenicity.

Deciphera Pharmaceuticals notes the article titled “Vimseltinib versus placebo for tenosynovial giant cell tumour (MOTION): a randomised phase 3 trial” is now available online and will be published in a future print issue of The Lancet.

“The completion of INSPiRE-ICU 2 concludes Sedana Medical´s clinical trials in the United States. Running this study together with esteemed clinical investigators from highly ranked academic centers such as Columbia, the Harvard-affiliated medical center Beth Israel Deaconess Medical Center and many others has been very exciting and rewarding. Many investigators from the participating sites have been excited to be part of our pioneering studies. The bedside experience in the studies has generated a lot of interest in using inhaled sedation in US practice, which we hope will be possible soon,” said Peter Sackey, Chief Medical Officer of Sedana Medical.

“Patient enrollment is the most time-consuming and costly aspect of the clinical trial process,” said Prem Batchu-Green, Vice President of Clinical at Viz.ai. “By deploying Viz.ai for the CHESS study, we are not only reducing the manual burden of patient identification on research staff but also improving SDH detection and workflow as well as increasing SDH awareness, physician engagement, clinical specialist attendance, and case collaboration.”