LayerBio Granted U.S. Patent for OcuRing™ Drug Delivery Platform

Novel sustained-release technology has potential to eliminate the need for eye drops after cataract surgery.

LayerBio, Inc. (LayerBio), an ophthalmology therapeutics company, announced today that the United States Patent and Trademark Office (USPTO) has issued US Patent No. 11,185,441.

“This patent issuance marks an important milestone for the OcuRing platform and recognition of novelty and uniqueness of our drug delivery technology,” said Kenneth Mandell, M.D., Ph.D., CEO and Founder of LayerBio. “LayerBio will continue to develop our portfolio of patents for the OcuRing platform in order to produce safer, more effective and better-tolerated alternatives to topical eye drops for patients undergoing cataract surgery.”

The patent provides coverage for a variety of drug product compositions, methods of use, and delivery systems for LayerBio’s propriety bioerodible drug delivery rings that release therapeutic medications for use in cataract surgery.

“OcuRing has the potential to transform the standard of care for cataract surgery,” said Dr. Richard Lindstrom, M.D., a leading expert in cataract surgery and member of LayerBio’s Board of Directors. “By automatically releasing medicine inside the eye after cataract surgery, OcuRing™ can ensure compliance, improve outcomes and enhance the overall patient experience.”

LayerBio’s lead product candidate OcuRing-K™ is a sustained-release nonsteroidal anti-inflammatory drug (NSAID) formulation of ketorolac, an opioid-sparing analgesic with proven efficacy for reducing inflammation and pain associated with cataract surgery.

“OcuRing-K is a game-changer because it provides all of the benefits of an NSAID without the ocular surface side effects,” said Dr. Eric Donnenfeld, M.D., chair of LayerBio’s medical advisory board. “By delivering ketorolac directly inside the eye, it maintains a therapeutic plateau and essentially eliminates the risks of surface corneal toxicity associated with NSAID eye drops.”

In addition to NSAIDs, the OcuRing™ platform has the capacity to deliver other ophthalmic medications, including corticosteroids, antibiotics and glaucoma medications. LayerBio will continue to develop innovative products that address unmet medical needs for cataract surgery and other eye conditions.

Hot this week

Cartessa Aesthetics Partners with Classys to Bring EVERESSE to the U.S. Market

Classys, which is listed on the KOSDAQ, is one of South Korea's most distinguished aesthetic technology manufacturers, with devices distributed in 80+ markets globally. This partnership marks Classys's official entry into the American marketplace, with Cartessa Aesthetics as the exclusive distributor for EVERESSE, launched under the Volnewmer brand in current global markets.

Stryker Launches Next-Generation of SurgiCount+

Now integrated with Stryker's Triton technology, SurgiCount+ addresses two key challenges: retained surgical sponges and blood loss assessment. Integrating these previously separate digital solutions provides the added benefit of a more efficient, streamlined workflow for hospitals notes Stryker.

Nevro Receives CE Mark In Europe for It’s HFX iQ™ Spinal Cord Stimulation System

Nevro notes HFX iQ is the first and only SCS system with artificial intelligence (AI) technology that combines high-frequency (10 kHz) therapy built on landmark evidence that uses ongoing cloud data insights to deliver personalized pain relief

Recor Medical Reports: CMS Grants Distinct TPT Device Code and Category to Recor Medical for Ultrasound Renal Denervation

The approval of TPT offers incremental reimbursement payments for outpatient procedures performed with ultrasound renal denervation for Medicare fee-for-service beneficiaries. It becomes effective January 1, 2025, and is expected to remain effective for up to three years notes Recor Medical.

Jupiter Endovascular Reports | 1st U.S. Patient Treated with Jupiter Shape-shifting Thrombectomy Device

“Navigation challenges during endovascular procedures are often underappreciated and have led to under-adoption of life-saving procedures, such as pulmonary embolectomy. We have purpose-built our Endoportal Control technology to solve these issues and make important endovascular procedures accessible to more clinicians and their patients who can benefit from them,” said Carl J. St. Bernard, Jupiter Endovascular CEO. “This first case in the U.S. could not have gone better, and appears to validate the safety and performance we are seeing in our currently-enrolling European SPIRARE I study.”