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NuVasive Specialized Orthopedics Surpasses 100 Peer-Reviewed Publications of the Precice System for Limb Lengthening

NuVasive, Inc. (NASDAQ: NUVA) today announced a milestone of more than 100 peer-reviewed publications of the Precice® System (Precice) for conditions related to limb lengthening and reconstruction from NuVasive Specialized Orthopedics™ (NSO). The Precice System is an intramedullary nail that once implanted, utilizes an External Remote Controller (ERC) to non-invasively lengthen the limb.

“This significant milestone further supports the benefits that Precice offers orthopedic surgeons and their patients,” said Dr. Stuart Green, orthopedic surgeon at UC Irvine School of Medicine. “First introduced in 2011, Precice has been used to successfully overcome limb length deficiencies in thousands of patients around the world with less pain and fewer complications than previously thought possible. The publications demonstrate the important role the implant plays in modern limb reconstruction—helping establish Precice as today’s standard of care.”

Following the first publication in 2014 in Clinical Orthopaedics and Related Research,1 more than 100 peer-reviewed publications have been authored in countries including the United States, Germany, and South Africa. Precice has been researched in dozens of journals including The Journal of Bone and Joint Surgery, Journal of Orthopaedic Trauma, Journal of the American Academy of Orthopaedic Surgeons, and The Journal of Surgical Orthopaedic Advances.

“With approximately 15,000 procedures in more than 45 countries, today’s announcement is yet another significant milestone for Precice,” said Pete Ligotti, general manager of NSO. “We remain committed to providing novel technology in underserved markets to help deliver better outcomes for surgeons—and most importantly for patients.”

NSO, a division of NuVasive, is focused on the design and innovation of disruptive orthopedic solutions for complex orthopedic reconstruction and limb lengthening. Precice is used to treat long bone abnormalities resulting from congenital bone conditions, oncology, or trauma. The proprietary technology includes a complex 60-piece internal gear system remotely activated and controlled by permanent rare earth magnets. This advancement in limb lengthening allows for a precision-controlled distraction phase with the ability to non-invasively customize treatment to best treat the patient’s individual needs.

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