TriAltus Bioscience Protein Purification Technology Supports Providence Cancer Institute COVID-19 Vaccine Development

Researchers at the Earle A. Chiles Research Institute, a division of Providence Cancer Institute, are using TriAltus Bioscience, LLC protein purification technology to fast-track development of an ELISA test to monitor antibody responses to SARS-CoV-2 in patients that will receive a COVID-19 vaccine.

The researchers are using TriAltus’ ultra-high-affinity CL7/Im7 system to isolate and purify the Spike protein (S-protein) from SARS-COV2 (COVID-19) and bind it to ELISA plates.

Named for its distinctive spike, the S-protein helps the COVID-19 virus attach to and infect human cells, leading to COVID-19 infections.

“We’re in a race to develop this vaccine as quickly as possible, so it’s important to have technology that helps us isolate and purify the S-protein for time-critical research,” said Hong-Ming Hu, Ph.D., Associate Member, Cancer Immunobiology Laboratory, Earle A. Chiles Research Institute. “The CL7/Im7 system enables our lab to isolate and purify the spike protein faster, with higher yields, thus saving precious time.”

Chiles Research Institute researchers are fast-tracking the development of a COVID-19 vaccine in collaboration with biotech company OncoSec, UbiVac and the National Institutes of Health. If all goes as expected, vaccine trials could begin in May.

“It’s rewarding to know that our product can help expedite the search for a COVID-19 vaccine,” said TriAltus Bioscience CEO Bob Shufflebarger. “Our CL7/Im7 system is helping Dr. Hu and his colleagues attain high protein purity in a single-step process that saves critical time and boosts research productivity.”

Simple, reusable and resilient, TriAltus’ Activated Im7 Resin has been used to purify a variety of proteins – including membrane, multisubunit, coronavirus, and Cas9 and Cas12a CRISPR-associated proteins. The Im7 resin is capable of up to 100 reactivations without loss of activity.

The CL7 technology was invented by a team led by Dmitry Vassylyev, Ph.D., TriAltus co-founder and professor of biochemistry and molecular biology at the University of Alabama Birmingham (UAB). The foundational study was published in 2017 in the Proceedings of the National Academy of Sciences. TriAltus offers a limited free sample program for researchers to validate the CL7/Im7 system in their own labs.

 

Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine provides our readership with breaking medical device / biotechnology news. Our subscribers include medical specialists, device industry executives, investors, and other allied health professionals, as well as patients who are interested in researching various medical devices. We hope you find value in our easy-to-read publication and its overall objectives! Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

More News!

Liviniti, a national PBM leader in transparency and prescription drug savings, announces a new collaboration with Mindera Health to improve management of moderate-to-severe psoriasis...
The collaborative study between Sheffield Hallam University and aims to gain a better understanding of Alzheimer's Disease (AD) in order to identify those more at risk of developing the disease, so enabling the provision of appropriate interventions much earlier in the disease pathology.
Today they announced that twelve new companies have entered its Venture Lab acceleration program for early-stage companies. The cohort is strategically aligned with BII’s focus on supporting innovative early-stage start-ups that can improve human and planetary health.
Michael Dabrowski, CEO of Pelago Bioscience "We are grateful to the University of Edinburgh in their acknowledgement of our Patent. I encourage the drug discovery community to engage with Pelago Bioscience to explore the value that our patented CETSA technology and services can bring to enhance their drug discovery efforts.
The Thermo Scientific™ Dionex™ Inuvion™ Ion Chromatography (IC) system, helping to make ion analysis simpler and more intuitive for labs of all sizes. The new analytical instrument is designed to be easily reconfigurable, providing those who require determination of ionic and small polar compounds with a one stop shop for consistent, reliable ion analysis.

By using this website you agree to accept Medical Device News Magazine Privacy Policy