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Sunday, June 4, 2023



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CorMatrix Cardiovascular Receives European Community and U.S. Patent Claim Allowances for Polymer Drug Delivery Prostheses

CorMatrix Cardiovascular, Inc., today announced European Patent Office patent claim allowances for European Community (EC) Patent Application Nos. 15 902 462.9 and 15 886 687.1, and U.S. Patent and Trademark Office patent claim allowance for U.S. Patent Application No. 16/531,263, which are directed to synthetic polymer drug delivery prostheses comprising unique biodegradable, non-inflammatory poly(glycerol sebacate) (PGS) particulate, and sheet structures.

CorMatrix Cardiovascular notes, the degradable polymer drug delivery prostheses are adapted to administer various drugs, such as antibiotics and anti-inflammatories, and biologically active agents, such as growth factors, to target tissue.

The European and U.S. Patent allowances will further enhance CorMatrix’s growing synthetic polymer and ECM (Extracellular Matrix) delivery platforms, which, in addition to PGS, includes poly(urethane urea), polylactide (PLA), poly(e-caprolactone) (PCL) and polyglycolide (PLGA) compositions and structures.

CorMatrix’s current synthetic polymer and ECM delivery platforms comprise over one-hundred and twenty (120) issued U.S. and foreign patents, and over thirty (30) pending U.S. and foreign patent applications.

“As a cardiovascular regenerative company, the addition of various polymers to our portfolio will substantially add to the breadth and latitude of our capabilities. Future devices from CorMatrix will be combinations of our substantial ECM capabilities and beneficial polymers also directing them additionally towards drug delivery,” said Robert Matheny, MD, Chief Scientific and Medical Officer of CorMatrix Cardiovascular.

Doug Boyd, MD, Chief of Cardiovascular Surgery at East Carolina University Medical Center added, “Several companies are using biodegradable polymers with drugs attached to deliver a localized vascular effect. You can see this in the vascular stenting business and drug-coated balloons to prevent restenosis. These patents will allow for the development of these devices for open and percutaneous surgeries for all kinds of heart and vascular diseases.”

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