Medical Device News Magazine

Saturday, April 1, 2023

CyberKnife® Robotic Radiotherapy Platform Recent Data

Published in the Journal of Neurosurgery: 7,000 Patient Single Institution Analysis Shows Safety, Versatility and Increasing Use of the Advanced Radiotherapy Platform Over a 20-Year Timeframe

Accuray Incorporated (NASDAQ: ARAY) announced today that more than two decades of globally-driven clinical data support the use of the company’s CyberKnife® robotic radiotherapy platform for the delivery of stereotactic radiosurgery (SRS) treatments for neurological diseases.

The most recent CyberKnife data, an analysis of 7,000 patients with brain or spinal lesions treated at Stanford University School of Medicine, was published online in the Journal of Neurosurgery. The non-invasive platform provides an approach for achieving excellent outcomes for a broad range of brain and spinal lesions and, as the analysis shows, is increasingly being used to expand the benefits of radiosurgery.

CyberKnife Radiotherapy: The Ultimate SRS Platform for a Diverse Patient Population
SRS was developed to provide a non-invasive approach for the treatment of intracranial lesions. Image guidance and software advances have improved the ability to target the radiotherapy beam, expanding the application of SRS to lesions in the brain and spine that were untreatable in the past.

The CyberKnife platform was developed in 1994 by Stanford University–based neurosurgeon John R. Adler, MD. Today, CyberKnife SRS is routinely used to treat a wide range of lesions – from brain and spinal metastases to benign and malignant primary lesions, functional diseases like trigeminal neuralgia and vascular disorders such as arteriovenous malformations. As the management of neurological conditions continues to evolve, it is expected that CyberKnife SRS will become an increasingly important component of the treatment regimen in recognition of the benefits it can provide. The platform delivers SRS with sub-millimeter accuracy and precision in just 1 to 5 sessions over 1 to 2 weeks, offering a shorter overall course of treatment for patients that may positively impact their quality of life and an option for medical teams to achieve their clinical efficacy and ROI goals.

“More than 25 years after the first brain tumor treatment with the CyberKnife platform, customers worldwide continue to identify new ways to leverage its unique architecture and push the boundaries of radiosurgery to improve their patients’ care,” said Jean-Philippe Pignol, M.D., Ph.D., chief medical & technology officer at Accuray. “The Journal of Neurosurgery analysis shows the platform can be used to treat a broad range of neurological conditions at various stages in the treatment journey – from first-line to adjuvant therapy and palliation – reinforcing its use in daily practice. The advantages of the platform’s robotic design and Synchrony® real-time image guidance make it an ideal choice for hospitals that want to offer exceptional care today and into the future.”

Accuray Proprietary Technology Designed to Deliver Better, Faster, Radiotherapy Treatments
Advanced functionality on the CyberKnife platform facilitates the delivery of precise treatments for more patients each day.

  • Next-generation Accuray Precision® Treatment Planning System (TPS) with the VOLO™ Optimizer
    • Reduces both the time to create high quality treatment plans and the time it takes to deliver them, making patients treatments significantly faster than with earlier versions of TPS
    •  Substantially reduces optimization time, supporting the creation of treatment plans for multiple cases in the same day, and helping to ensure the optimal plan is created for neurology and cancer cases spanning different diagnoses and tumor sizes
  • Artificial intelligence (AI)-driven Synchrony® Technology
    • Synchronizes the radiation beam to the target in real-time, maximizing dose to the lesion while minimizing dose to surrounding healthy structures
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