Tele: 561.316.3330
Breaking Medical Device News

Wednesday, October 20, 2021


HomeBIOTECHNOLOGYRebus Biosystems Launches Automated Spatial Omics Platform

Rebus Biosystems Launches Automated Spatial Omics Platform


Global $45 Billion Endoscopy Market Insights & Forecasts to 2025

The global endoscopy market is predicted to reach US$45.28 billion in 2025, growing, at a CAGR of 7.50%, for the duration spanning 2021-2025.

Global Remote Monitoring Devices Market Research Report (2021 to 2026)

Global Remote Monitoring Devices Market size was estimated at USD 1,035.35 million in 2020, is expected to reach USD 1,170.22 million in 2021.

Research Efforts Fuel the Future of Global Obstructive Lung Disease Management Markets –

The "Global Obstructive Lung Disease Management Research Report" report has been added.

Global Electrophysiology Market (2021 to 2026) – Growth, Trends , COVID-19 Impact and Forecasts –

The Electrophysiology Market is expected to register a CAGR of 8.5% during the forecast period.

Rebus Biosystems, Inc., a life science technology company creating revolutionary tools to enable spatial omics research without compromise, today announced the launch of the Rebus Esper™ spatial omics platform.

The new spatial omics platform will allow researchers to better understand the biology of tissues and lead to advancements in neuroscience, cancer, infectious disease and immunology.

Launched at the Advances in Genome Biology and Technology (AGBT) virtual meeting, the Rebus Esper leverages the unique capabilities of Rebus Biosystems’s patented Synthetic Aperture Optics (SAO) technology, a super-resolution technique that allows routine quantitative analysis of tens of millions of cellular features across hundreds of thousands of cells.

“The Rebus Esper brings a whole new dimension to biological research. This fully integrated, automated instrument delivers high-throughput, quantitative, single-molecule, single-cell data with spatial context and subcellular resolution by bringing together advancements in imaging, fluidics, chemistry and bioinformatics,” said Paul Sargeant, Ph.D., CEO of Rebus Biosystems. “Whereas other methods for spatial omics analysis require tradeoffs between quality and throughput, the Rebus Esper platform delivers an unprecedented combination of resolution, scale and speed in a single instrument with walkaway operation.”

The Rebus Esper instrument is incredibly easy to use. No experience with imaging or image processing is required. Preparing a run follows a simple protocol that requires less than one hour of hands-on time. Using the instrument is as easy as loading the reagents and flow cell, starting the run, and coming back at the end to collect processed data that is ready for single-cell analysis and precise spatial mapping.

“We have been using the Rebus Esper platform to look at how genes are different in terms of their spatial position across different brain regions. It has allowed us to visualize our data with high sensitivity across individual tissue sections, as well as across different samples,” said Aparna Bhaduri, Ph.D., Assistant Professor of Biological Chemistry at the David Geffen School of Medicine at UCLA. “The number of genes, the speed of data collection, and the ability to image large areas has enabled us to look at more genes across more tissue than any other method currently available.”

“We are delighted with the early excitement we’ve seen in the market for our platform and pleased to now offer this technology to customers worldwide to bring into their own labs,” said Sargeant. “We’re especially excited to bring the multi-assay capabilities of the Rebus Esper platform to the field of spatial omics. Researchers can choose the assays best suited to answering their research questions and run them all on a single easy-to-use instrument.”

The first assay to be released for the Rebus Esper platform is the Esper™ High Fidelity assay. This ultra-sensitive assay, based on cyclic single-molecule fluorescent in situ hybridization (smFISH) chemistry, can resolve and map individual RNA molecules in their original locations, giving researchers a complete picture of tissues across a wide range of expression levels for up to thirty custom genes.

Rebus Biosystems plans to rapidly expand the assay menu for the Rebus Esper platform. During 2021, the Esper High Fidelity suite of assays will enable a higher level of multiplexing and protein co-detection.  In addition, the company will focus on developing assays enabling multiplex gene expression in formalin-fixed, paraffin embedded (FFPE) samples and simultaneous analysis of over 1000 genes.



Children Achieve Time in Range Mirroring Well-controlled Adults for the 1st Time in Real-world Study of the MiniMed™ 780G System

"These results are extremely encouraging. Glycemic control has been much harder to achieve in children due to unpredictable factors common in this age group, including physical growth and development, hormonal changes and active lifestyles.

Aethlon Medical Announces Peer-Reviewed Publication of Two Case Studies of Critically Ill COVID-19 Patients Treated with the Hemopurifier®

The publication documents two critically ill COVID-19 patients receiving a combined total of nine, six-hour Hemopurifier® treatment sessions.

Koya Medical Presents Positive Interim Data from Randomized Trial Comparing its Dayspring Lymphedema Treatment to Pneumatic Compression

For people with lymphedema, movement is important from both a clinical perspective and a quality-of-life perspective. These data illustrate the Dayspring treatment’s ability to provide that essential movement while still delivering the clinical outcomes we need from compression therapy.

Our Sister Publication: Biotechnology News Magazine

By using this website you agree to accept Medical Device News Magazine Privacy Policy