Medical Device News Magazine

TSC Alliance Applauds Release of Updated International Guidelines for Tuberous Sclerosis Complex Diagnostic and Management Recommendations

About Medical Device News Magazine

About Medical Device News Magazine. We are a digital publication founded in 2008 located in the United States.

Advertise with Medical Device News Magazine! Join Our #1 Family of Advertisers!

We pride ourselves on being the best-kept secret when it comes to distributing your news! Our unique digital approach enables us to circulate your...

TSC Alliance announced the publication of two new papers in the prestigious Pediatric Neurology: “Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations” and “Beyond the Guidelines: How We Can Improve Healthcare for People with Tuberous Sclerosis Complex Around the World.”

 

Tuberous sclerosis complex (TSC) causes tumors to grow in different organs and can impair their function, primarily the brain, heart, kidneys, skin and lungs. Changes in the brain caused by TSC have the biggest impact on quality of life, from seizures and developmental delays to intellectual disabilities, behavioral challenges and autism.

“The TSC Alliance is thrilled to announce updated ‘gold standards’ for TSC diagnosis, surveillance and management,” said President & CEO Kari Luther Rosbeck. “The updated guidelines recognize the value of early surveillance and intervention. We look forward to the day we can prevent the most impactful aspects of TSC rather than waiting to treat them after they occur.”

The new papers provide the first significant updates to the international guidelines since 2013 because of new medications and advances in treatments since then. To address the changes, a working group led by Darcy A. Krueger, MD, PhD, of Cincinnati Children’s Hospital Medical Center, and Hope Northrup, MD, McGovern Medical School, University of Texas Health Science Center at Houston, included 80 participants from 16 countries.

Additionally, TSC International, a consortium of organizations that support individuals with TSC around the world, penned the companion piece, “Beyond the Guidelines: How We Can Improve Healthcare for People with Tuberous Sclerosis Complex from Around the World.” This paper examines the state of TSC care around the world, identifies gaps in TSC care and makes recommendations for how TSC organizations and key stakeholders can work together to overcome barriers in TSC care.

With an emphasis on the need for greater access to specialized TSC and comprehensive coordinated care, most recommendations for diagnosis, surveillance and management of TSC remained consistent with previous guidelines, but some major changes were made, including:

  • Increased emphasis on early screening for EEG abnormalities, which could indicate impending epilepsy and higher risk for poorer developmental outcomes.
  • Increased understanding of TSC-Associated Neuropsychiatric Disorders (TAND) and the need to identify and address issues to enable appropriate support. The concept of TAND was born at the 2012 TSC Consensus Conference, and these updated guidelines reflect how much has been learned about the importance of accurately and urgently dealing with TAND and many other aspects of TSC in the last nine years.
  • Regulatory approval in the United States and many other countries since 2013 of everolimus for adjunctive treatment of focal-onset seizures in TSC, cannabidiol for epilepsy in TSC and sirolimus for lymphangioleiomyomatosis, a lung disease that affects women more often than men, usually between the onset of puberty and menopause.

“The TSC Alliance is grateful for the leadership of Drs. Northrup and Krueger and for the collaboration and contributions of international experts and advocates to make this happen,” explained Steven L. Roberds, PhD, Chief Scientific Officer. “As we gather data on the implementation and outcomes of these recommendations, we plan to develop and continually update evidence-based guidelines.”

In addition to the new papers, a continuing medical education course from the Peerview Institute for Medical Education, “Applying Evidence to Practice–Updated Consensus Recommendations for the Diagnosis, Surveillance, and Management of Tuberous Sclerosis Complex,” is also available.

The TSC Alliance is an internationally recognized nonprofit that does everything it takes to improve the lives of people with TSC. It drives research, improves quality care, works to increase access and advocates for all affected by the disease.

 

 

Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine provides breaking medical device / biotechnology news. Our subscribers include medical specialists, device industry executives, investors, and other allied health professionals, as well as patients who are interested in researching various medical devices. We hope you find value in our easy-to-read publication and its overall objectives! Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

Other News

Radical Catheter Technologies Presents Analysis of Disruptive, Recently FDA-Cleared Endovascular Technology at the Society of NeuroInterventional Surgery 21st Annual Meeting

This new catheter, the first product commercialized from this novel technology platform, is designed to enable access to the blood vessels in the brain for both femoral and radial access. A multi-center analysis of this disruptive technology is being presented today at Society of NeuroInterventional Surgery 21st annual meeting. In addition, the Company confirmed the closing of a $20 million financing round led by NeuroTechnology Investors, which will be used to scale the company and expand the Radical platform notes Radical Catheter Technologies.

Rapid Medical™ Completes Initial Neurovascular Cases in the USA Following FDA Clearance of Its Active Access Solution

“With DRIVEWIRE, our design goal was to bring new levels of access and control to the interventional suite while improving best-in-class guidewires,” comments Giora Kornblau, Chief Technology Officer at Rapid Medical. “When physicians are looking for technologies that increase the clinical possibilities and safety for the patient, we want Rapid to be the first place they look.”

HeartFlow Introduces Next Generation Interactive Plaque Analysis Platform to Assess Patient Risk in Suspected Coronary Artery Disease

The HeartFlow Plaque Analysis uses proprietary algorithms to analyze coronary CT angiogram (CCTA) scans, creating a personalized 3D model that quantifies and characterizes plaque volume in the coronary arteries, aiding risk assessment of coronary artery disease. The technology was introduced at the Society of Cardiovascular Computed Tomography (SCCT) Annual Scientific Meeting in Washington, D.C.