Ultra-low Contrast PCI Solutions: Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, is showcasing innovations at EuroPCR (May 17-20, Paris, France) that can enable interventionists to perform ultra-low contrast percutaneous coronary intervention procedures with greater confidence and clarity.
Philips’ ultra-low contrast PCI solutions co-register instantaneous blood flow measurements and/or intravascular ultrasound (IVUS) images onto real-time fluoroscopy to help interventionists diagnose, decide, guide, treat and confirm the success of PCI, with the potential to limit the use of iodinated contrast media.
Seamlessly integrating into Philips’ Image Guided Therapy System – Azurion – the company’s unique ultra-low contrast PCI solutions provide physicians with tools to help reduce the use of contrast media throughout PCI procedures.
The ability to perform PCI procedures using a very small amount of contrast media enables PCI to be offered to more patient groups, notably patients presenting with both coronary artery disease (CAD) and chronic kidney disease (CKD), who are at high risk of suffering contrast-induced nephropathy (CIN) [1] – a life-threatening form of hospital-acquired acute kidney injury (AKI) caused by contrast media toxicity. A 2020 study in the USA concluded that AKI after a PCI procedure resulted in an average increase in length of hospital stay of 3.6 days and an additional healthcare cost of 9,448 USD per patient [2].
Dynamic Coronary Roadmap
During a conventional PCI procedure, contrast media is injected into the patient’s coronary arteries to acquire an angiogram, with additional fluoroscopy used during the procedure to help interventionists navigate their guide wires and catheters. To maintain visibility of the arteries, this guidance typically requires repeated contrast media injections, increasing the toxic load on the patient’s kidneys. Philips’ Dynamic Coronary Roadmap software removes the need for additional contrast media injection by overlaying the preoperative angiogram onto real-time motion-compensated 2D fluoroscopic imaging to provide interventionists with continuous visual feedback on the positioning of guide wires and catheters. In many cases, no additional contrast media injection is required for wire navigation.
While Philips’ Dynamic Coronary Roadmap software helps interventionists navigate guide wires and catheters to the site of a lesion, the company’s IntraSight Series 7 precision guidance system streamlines lesion assessment, simplifies vessel sizing, and enables precise therapy delivery.
iFR Co-registration
IVUS Co-registration
Tri-registration
Ultra-Low Contrast PCI at EuroPCR
Professor Javier Escaned, together with other key thought leaders in the field of UCL-PCI, will discuss how to decrease operator dependence on vessel opacification during PCI in a Philips-sponsored symposium at EuroPCR 2022 on Tuesday, May 17, from 17:15 to 18:15 (CET).
[1] Dangas G, et al. Contrast-Induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables. AJC 2005. https://doi.org/10.1016/j.amjcard.2004.08.056.
[2] Amin P, et al. Incremental cost of Acute Kidney Injury after Percutaneous Coronary Intervention in the United States. AM J Cardiol. 2020 Jan1;125(1):29-331.
[3] Costa et al. Impact of Stent Deployment Procedural Factors on Long-term Effectiveness and Safety of Sirolimus-Eluting Stents (Final results of the Multicenter Prospective STLLR Trial), Am J Cardiol 2008 Jun 15; 101(12):1704-11.