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First Implants of PROPEL Contour in Patients with Chronic Rhinosinusitis Following Frontal Sinus Surgery in Europe

PROPEL Contour: Intersect ENT®, Inc. (Nasdaq: XENT), a global ear, nose and throat (“ENT”) medical technology leader dedicated to transforming patient care, today announced that Helios Dr. Horst Schmidt Kliniken Wiesbaden in Germany was the first hospital outside the United States to offer the Company’s PROPEL® Contour (mometasone furoate) sinus implant following functional endoscopic sinus surgery (FESS). FESS is used to treat chronic rhinosinusitis, a persistent inflammation of the sinuses that can be debilitating to patients.

Intersect ENT’s PROPEL Contour is a drug-eluting, bioabsorbable sinus implant that is placed in the frontal sinus (between the eyebrows) following sinus surgery. PROPEL Contour incorporates a unique hourglass design that conforms to the sinus openings that delivers an advanced corticosteroid with anti-inflammatory properties and mechanical support to help improve surgical outcomes. PROPEL Contour is clinically proven to reduce the need for additional interventions (surgical treatments and/or oral steroids) after sinus surgery by 65 percent.1 PROPEL Contour is the third localized drug delivery implant (inclusive of PROPEL and PROPEL Mini), completing the PROPEL family of drug-eluting, bioabsorbable implants now available to ENT specialists in select EU countries.

“After treating my first two patients with PROPEL Contour post-functional endoscopic sinus surgery in August 2021, I was pleased with the design of the PROPEL Contour sinus implant for patients with variable frontal sinus openings that are suffering from chronic rhinosinusitis,” said Prof. Dr. Jan Gosepath, Chairman, Department of Otolaryngology, Head and Neck Surgery, Helios HSK Wiesbaden and Medical Director, Helios Dr. Horst Schmidt Privatklinik Wiesbaden. “With this implant, the surgically enlarged sinus opening can be maintained, and the steroid can be delivered directly to the site where it is needed most to improve postoperative outcomes. At 4-weeks follow-up, both patients showed excellent wound healing, which is what I like to see. Another benefit of the PROPEL Contour implant is that it does not need to be removed and will dissolve after approximately 4-6 weeks.”

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