Tele: 561.316.3330
Breaking Medical Device News

Monday, September 27, 2021
HomeNON PROFITNovel Antioxidant Can Provide a Number of Health Benefits for Peripheral Artery Disease According to 11 Patient Published Study

Novel Antioxidant Can Provide a Number of Health Benefits for Peripheral Artery Disease According to 11 Patient Published Study

November 20, 2020

Novel antioxidant can provide a number of health benefits for individuals with peripheral artery disease according to researchers at the School of Health and Kinesiology at the University of Nebraska at Omaha.

Novel antioxidant specifically targets mitochondria, considered the powerhouse of the cell. The study was led by Assistant Professor Song-Young Park, Ph.D., and published in the American Journal of Physiology-Heart and Circulatory Physiology.

Park recruited eleven men and women with PAD to participate in this research; six of which received 80 milligrams of the antioxidant while the remaining five participants were given a placebo. Measurements were done before and 40 minutes after each participant took the supplement or placebo to assess the roles of vascular mitochondria in endothelial function, arterial stiffness, exercise tolerance, and skeletal muscle function. After a 14 day “wash out” period, the two groups switched, with the placebo group taking the supplement and vice versa, and measurements were assessed again.

When a participant took the supplement, the researchers noted an increase in dilation of the arteries, popliteal flow-mediated dilation, antioxidant superoxide dismutase, maximal walking time and distance, and time to claudication or leg pain.

“The results of this study reveal for the first time that acute oral intake of a mitochondrial-targeted antioxidant is effective for improving vascular endothelial function and superoxide dismutase in patients with peripheral artery disease (PAD),” Park said. “This improvement is clinically important and such antioxidants may potentially be utilized as therapeutic supplement for patients with PAD”.

The novel antioxidant, commercially available as MitoQ, contains the naturally occurring ubiquinol which is a coenzyme that gives the antixoxidant the ability to cross the cell membrane and accumulate within the mitrochondria.

Peripheral artery disease (PAD) is a common cardiovascular disease in which atherosclerotic plaque forms in the arteries of the leg which can cause decrease blood flow and reduced perfusion in the lower extremity. The disease affects nearly 200 million people worldwide, with over 20 percent of individuals over 80 years old being affected by this disease. Common symptoms often include foot ulcers and leg pain during walking. If severe, medical treatment up to and including leg amputation may be required.

This study was funded in part by the University of Nebraska at Omaha Graduate Research and Creative Activity (GRACA) grant awarded to Jiwon Song, University of Nebraska at Omaha University Committee on Research and Creative Activity (UCRCA) awarded to Song-Young Park and the NASA Nebraska Space Grant (#NNX15AI09H) awarded to Song-Young Park. Doses of MitoQ were donated to UNO by MitoQ Limited for use in this research study.

Medical benefits

Medical Device News Magazinehttps://infomeddnews.com
Medical Device News Magazine is a division of PTM Healthcare Marketing, Inc. Pauline T. Mayer is the managing editor.

Stay Connected

spot_img

Don't Miss

ProSomnus® Sleep Technologies Adds John E. Remmers, MD, to Leadership Team

Dr. John E. Remmers will provide expert medical and strategic guidance on a range of initiatives, including research and development, regulatory clearances, company strategy, medical education, and clinical investigations.

Nanox to Announce Zebra Medical Vision Secures 8th 510K FDA Clearance for its Coronary Artery Calcium (CAC) Solution as Part of Its Population Health Offering

On August 10th, 2021 Nanox announced that it had entered into an acquisition agreement via merger with Zebra Medical Vision LTD.

Christopher Joyce Joins Miach Orthopaedics as VP & CFO

Christopher Joyce has joined as vice president and chief financial officer, and Kevin Sidow has been appointed to the company’s board of directors.

NGMedical GmbH Receives FDA Clearance for Its AM Titanium Lumbar Interbody BEE® PLIF

The BEE® PLIF cage has been created to benefit from additive manufacturing features. The purposefully designed honeycomb endplate design reduces the risk of subsidence, while allowing fusion.

Recombinant Technologies is Raising Capital to Roll Out a Game Changing Alzheimer’s Treatment

Recombinant Technologies is focused on treating the root cause of Alzheimer's Disease delivering a huge improvement in the quality of life of those afflicted.

Tyber Medical Reaches Agreement to Acquire CatapultMD

Once the acquisition is complete, Tyber Medical will own and operate a combined 100,000-square feet of manufacturing space between its Pennsylvania headquarters and Florida-based facilities.

Kleiner Device Labs Receives FDA Market Clearance for KG2 Surge Flow-Thru Interbody System

The system maximizes total bone graft delivery volume, better distributes graft bilaterally into the intervertebral disc space, and streamlines the implant delivery, positioning, and grafting process for TLIF and PLIF spinal fusion procedures.

Matthew Cranfill New ExtriCARE USA Director Of Clinical Services

"Matt's impressive experience and skillset easily made him our top pick," said Peter Mason, President of ExtriCARE USA.

By using this website you agree to accept Medical Device News Magazine Privacy Policy