Phage-Derived Enzyme Targets E. faecalis Biofilms to Mitigate Acute Graft-Versus-Host Disease
In a recent study published in the journal Nature, our researchers have identified a bacteriophage-derived enzyme called endolysin that targets Enterococcus faecalis biofilms. This discovery offers a promising new approach to mitigating acute graft-versus-host disease (aGVHD) in patients undergoing stem cell transplantation. The enzyme’s ability to specifically target harmful bacteria without affecting beneficial ones could revolutionize treatments for aGVHD.